Serum uric acid is not an independent risk factor for coronary heart disease |
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| Authors: | S Goya Wannamethee PhD |
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| Institution: | (1) Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, NW3 2PF London, UK |
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| Abstract: | Many large epidemiologic studies have confirmed a positive association between raised serum uric acid and risk of coronary
heart disease or cardiovascular disease, both in the general population and among hypertensive patients. There is much controversy
concerning the role of uric acid as an independent risk factor in the development of coronary heart disease because serum
uric acid is related to many of the established etiologic risk factors for cardiovascular disease that could confound the
observed association. This review finds little support for an independent causal role for serum uric acid in the development
of coronary heart disease. |
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