| 女性高血压人群血脂水平与缺血性卒中的相关性 |
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| 引用本文： | 杨红梅,张心刚,郑黎强,孙兆青,孙英贤.女性高血压人群血脂水平与缺血性卒中的相关性[J].山东医药,2009,49(47):18-20. |
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| 作者姓名： | 杨红梅 张心刚 郑黎强 孙兆青 孙英贤 |
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| 作者单位： | 1. 中国医科大学附属第一医院,沈阳,110001
2. 中国医科大学附属第二医院 |
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| 基金项目： | 辽宁省科技攻关重点项目 |
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| 摘 要： | 目的 探讨女性高血压人群血脂水平与缺血性卒中的关系。方法对3607例女性原发性高血压病患者进行流行病学调查和实验室检查，通过Logistic回归获得各类血脂水平对缺血性卒中的风险率及95％可信区间（a）。结果调整各种混杂因素后，非高密度脂蛋白胆固醇（non-HDL-C）和总胆固醇与高密度脂蛋白胆固醇比率（TC／HDL—C）与缺血性卒中显著相关，OR分别为1．253（95％CI，1．039～1．512）和1．594（95％C1，1．267～2．006）。结论non-HDL和TC／HDL—C是女性高血压人群缺血性卒中独立的预测因子。
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| 关 键 词： | 胆固醇 血脂 脑卒中 高血压 |
Correlation between the level of blood lipids and the risk of ischemic stroke in women with hypertension |
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| YANG Hong-mei,ZHANG Xin-gang,ZHENG Li-qiang,SUN Zhao-qing,SUN Ying-xian.Correlation between the level of blood lipids and the risk of ischemic stroke in women with hypertension[J].Shandong Medical Journal,2009,49(47):18-20. |
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| Authors: | YANG Hong-mei ZHANG Xin-gang ZHENG Li-qiang SUN Zhao-qing SUN Ying-xian |
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| Institution: | YANG Hong-mei , ZHANG Xin-gang, ZHENG Li-qiang, SUN Zhao-qing, SUN Ying-xian ( 1 The First Hospital Affiliated to China Medical University, Shenyang 110001, P. R. China) |
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| Abstract: | Objective To evaluate the correlation between the level of blood lipids and the risk of ischemic stroke in women with hypertension. Methods An epidemiological studies and laboratory assess to a resident group of 3 607 women with hypertension were conducted. Odds ratios （OR） and 95% confidence intervals （CI） for ischemie stroke were calculated by using logistic regression. Results After adjusting for independent variables, non-HDL cholesterol （non-HDL-C） and TC： HDL-C ratio had a significant association with ischemic stroke. The adjusted OR and CI were 1. 253 （95% CI, 1.039-1.512） and 1.594（95%CI, 1.267-2.006） respectively. Conclusions Non-HDL-C and TC： HDL-C ratio are the independent risk factor for ischemic stroke in women. |
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| Keywords: | cholesterol lipids stroke hypertension |
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