| 高同型半胱氨酸血症与老年冠心病 |
| |
| 引用本文： | 戚本玲,张银环,郭和平,管思明,张湖平,彭雯.高同型半胱氨酸血症与老年冠心病[J].临床心血管病杂志,2001,17(8):358-359. |
| |
| 作者姓名： | 戚本玲 张银环 郭和平 管思明 张湖平 彭雯 |
| |
| 作者单位： | 1. 华中科技大学同济医学院附属协和医院老年病科
2. 华中科技大学同济医学院附属协和医院心血管生化研究室 |
| |
| 摘 要： | 目的 :探讨高同型半胱氨酸 (HCY)血症与冠心病 (CHD)的关系及其可能的机制。方法 :选择 112例CHD患者 (CHD组 ) ,34例健康体检者 (对照组 ) ,分别测定血浆 HCY、活化的部分凝血活酶时间 (APTT)、血浆凝血酶原时间 (PT)、纤维蛋白原 (FIB)。结果 :CHD组血浆 HCY较对照组显著升高。高 HCY的 CHD组中 APTT、PT较正常 HCY的 CHD组及对照组组显著减低 ,而 FIB则显著升高。结论 :高 HCY血症与 CHD密切相关 ,并通过影响血凝状态而参与 CH D的发生及发展
|
| 关 键 词： | 冠状动脉疾病 高同型半胱氨酸 |
| 文章编号： | 1001-1439(2001)08-0358-02 |
| 修稿时间： | 2001年3月18日 |
Homocysteine and coronary heart disease |
| |
| QI Benling,ZHANG Yinhuan,GUO Heping,GUAN Siming,ZHANG H uping,PENG Wen.Homocysteine and coronary heart disease[J].Journal of Clinical Cardiology,2001,17(8):358-359. |
| |
| Authors: | QI Benling ZHANG Yinhuan GUO Heping GUAN Siming ZHANG H uping PENG Wen |
| |
| Institution: | QI Benling1 ZHANG Yinhuan1 GUO Heping2 GUAN Siming1 ZHANG H uping1 PENG Wen1 |
| |
| Abstract: | Objective:To investigate the ac tion of homocysteine in coronary heart disease.Method:One hundred and twelve CHD patients were enrolled as CHD group and 34 health as control (C) group. The plasma levels of HCY, APTT, PT and FIB were measured.Result: Plasma level of HCY was higher significantly in CH D group than that in C group. Plasma levels of APTT and PT were lower in CHD gro up than those in C group. Plasma levels of APTT and PT in CHD group with higher HCY were lower significantly than those in CHD group with normal HCY and C group . But plasma level of FIB was higher in CHD group than that in C group.Conclusion:Homocysteine may be an importent risk factor of CHD, and it can accerelated blood coagulation. |
| |
| Keywords: | Coronary disease Homocysteine |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
