比浊法在线自动测定红霉素片的效价 |
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引用本文: | 汪正宇.比浊法在线自动测定红霉素片的效价[J].中国现代医生,2010,48(22):81-82. |
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作者姓名: | 汪正宇 |
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作者单位: | 安徽省宿州市药品检验所,安徽宿州,234000 |
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摘 要: | 目的建立测定红霉素肠溶片效价的方法。方法采用比浊法测定红霉素的效价,并与管碟法比较。结果红霉素检测浓度的线性范围为(0.09~1.0)IU/mL(R2=0.998);回收率为98.33%~102.67%(RSD=1.46%);比浊法与管碟法的测定结果比较,差异无统计学意义。结论本方法操作更快捷、方便。
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关 键 词: | 比浊法 红霉素肠溶片 效价测定 |
Automatic Determination of Titer of Erythromycin Tablets by Turbidimetry |
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Authors: | WANG Zhengyu |
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Institution: | WANG Zhengyu Suzhou Institute of Drug Control in Anhui Province,Suzhou 234000,China |
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Abstract: | Objective To establish a method to determine the titer of erythromycin enteric tablets.Methods Turbidimetry was used to determine the titer of erythromycin tablets and turbidimetry was compared with cup-plate method.Results The linearity range of the erythromycin detection concentration was 0.09~1.0IU·mL-(1R2=0.998),and its recovery rate was 98.33%~102.20%(RSD=1.46%).There was no significant difference in the determination results of two kinds of methods.Conclusion Turbidimetry is proved to be more rapid and convenient than the cup-plate method. |
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Keywords: | Turbidimetry Erythromycin tablets Titer determination |
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