Omental deposits surveillance in gynecological malignancies at first setting follow up: 18F-FDG PET/CT compared to CT

Objective

The aim of this study was to compare the diagnostic performance of positron emission tomography/computed tomography (PET/CT) scan and CT scan in follow up of proven gynecological malignancies omental deposits in first setting follow up after treatment.

Patients and methods

60 female patients having proven omental deposits from gynecological malignancies underwent PET/CT examination following a preset protocol as baseline study. 34 cases of them had a second PET/CT examination following same protocol after 5–11 months considered as first setting follow up study aiming to assess therapeutic response.

Results

Out of 34 cases 2 cases (6%) showed only newly developed lesions, 8 cases (23.5%) showed progression, 8 cases (23.5%) showed mixed response and 16 cases (47%) showed regression or complete resolution. In first setting follow up examination ¹⁸F-FDG PET/CT showed 31 TP, 2 TN and 1 FN cases while CT showed 29 TP, 2 TN, 2 FN and 1 FP cases. ¹⁸F-FDG PET/CT vs. CT revealed sensitivity, specificity and accuracy of 96.88% vs. 93.55%, 100% vs. 66.67% and 97.06% vs. 91.18% respectively.

Conclusion

¹⁸F-FDG PET/CT is more accurate than CT in assessment of therapeutic response of proven gynecological malignancies omental deposits in first setting follow up.