总胆红素与老年高血压患者低密度脂蛋白及白蛋白关系的探讨

目的探讨血清总胆红素与老年高血压患者低密度脂蛋白、白蛋白的关系。方法243例老年人，单纯高血压组60例，高血压肥胖组62例，对照组121例。测定3组的血清总胆红素、白蛋白、甘油三酯、高密度脂蛋白胆固醇、总胆固醇、低密度脂蛋白胆固醇，并对数据进行分析。结果老年男性总胆红素高于老年女性，总胆红素与老年男性白蛋白及老年女性低密度脂蛋白胆固醇正相关。单纯高血压组老年男女总胆红素低于对照组，男性单纯高血压组与对照组比较差异有显著性意义；女性则差异无显著性意义。单纯高血压组老年人低密度脂蛋白胆固醇低于、高血压肥胖组老年人高于对照组，但差异无显著性意义。老年男性高血压组总胆红素与低密度脂蛋白胆固醇不相关，老年女性单纯高血压组总胆红素与低密度脂蛋白胆固醇正相关，与白蛋白不相关。结论老年女性高血压患者总胆红素随低密度脂蛋白胆固醇水平的增高而增高，血清白蛋白与老年男性总胆红素有关联。性别及增龄对高血压患者总胆红素水平可能有一定影响。

Relationship between serum total bilirubin and low-density lipoprotein,albumin in elderly patients with hypertension

Objective To study the relationship between serum total bilirubin（T-Bili） and low-density lipoprorein（LDL-C）, serum albumin in elderly patients with essential hypertension. Methods We selected 60 patients with essential hypertension only（ hypertension I group）, 62 overweight or obese senile people with essential hypertension （ hypertension Ⅱ group） and 121 healthy control subjects （ control group）. The T-Bili, Alb, LDL-C, TG, HDL-C and TC of all cases were determined and statistical analyses were performed. Results The T-Bili was higher in elderly men than that in elderly women（P（0. 05）. Compared with control group, the male hypertension I group showed lower T- Bili level（ P（0. 05）. There was positive correlation between T-Bill and LDL-C in elderly women（P〈0. 05） as well as serum albumin in elderly men（ P〈0. 05）. The T-Bill also had positive correlation with LDL-C in female hypertension I group（P（0. 05）. There was no correlation between T-Bill and LDL-C in male hypertension subjects. Conclusion The level of T-Bili appears to increase along with rising of LDL-C in elderly women with hypertension. There is a correlation between T-Bill and concentration of serum albumin in elderly male. Gender and aging may affect the T- Bili level in hypertension subjects.