急诊重症监护病房院内获得性细菌感染临床调查

目的:明确急诊重症监护病房(EICU)院内获得性细菌感染的病原分布概况和抗菌药物的敏感性,指导临床经验性使用抗菌药物。方法:自2005年1月-2008年12月,对我院急诊科重症监护病房患者院内获得性细菌感染及其抗菌药物的敏感性进行回顾性调查。结果:院内获得性细菌感染,其中G-菌占46.95%,G+菌占29.89%,真菌占22.56%;G-菌主要为铜绿假单胞菌、鲍曼不动杆菌、阴沟肠杆菌、大肠埃西菌、克雷伯菌属菌株,G-杆菌仍对亚胺培南保持着较高的敏感率。G+菌主要为金黄色葡萄球菌、凝固酶阴性葡萄球菌、肠球菌属菌株,万古霉素保持着对革兰阳性感染菌100%的抗菌活性。结论:根据细菌病原学及抗菌药物敏感性的临床资料,合理选择经验性抗菌药物,减少耐药菌的出现。

Nosocomial infection in EICU:A clinical investigation

Objective：To investigate the distribution and pathology of EICU nosocomial infection and the antibiotics sensitivity information,and to provide the guidance for empirical use of antibiotic.Method：The bacterial isolates from EICU nosocomial infection and their antibiotic susceptibility were retrospectively analyzed from January 2005 to Dec 2008 in our hospital.Result：Among the isolated pathogens,Gram negative bacteria and Gram positive bacteria were 46.95% and 29.89% respectively.Fungi were 22.56%.Gram negative bacteria mainly included Pseudomonas aeruginosa,A.baumannii,Ent.cloacae,Eschenchia and Klebsialla spp.Gram positive bacteria mainly included Staphylococcus aureus,Coagulase negative staphylococci and Enterococcus.The Gram negative bacteria showed high susceptibility to imipenem and Gram-positive bacteria were susceptive to vancomycin.Conclusion：In order to control the infection in EICU and decrease the emergence of the drug resistant bacteria,we should select antibiotics reasonably according to the data of the bacterial pathology and the antibiotics susceptibility.