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血清肌钙蛋白Ⅰ对急性心肌梗死早期诊断的临床价值
引用本文:王莹超. 血清肌钙蛋白Ⅰ对急性心肌梗死早期诊断的临床价值[J]. 中国血液流变学杂志, 2006, 16(2): 286-287
作者姓名:王莹超
作者单位:苏州市立医院北区检验科,江苏,苏州,215008
摘    要:目的观察急性心肌梗死(AMI)患者入院前后血清肌钙蛋白I(cTnI),心肌肌酸激酶同工酶MB(CK-MB)测定值的变化。探讨cTnI对早期诊断AMI的价值。方法对50例AMI患者和50例健康人血清进行cTnI和CK—MB的检测。结果 AMI后3h内cTnI阳性检出率94.0%,明显高于CK-MB24.0%,AM15d后cTnI阳性84.0%,而CK-MB仅为6.0%。结论血清cTnI能早期确切诊断AMI,具有较宽的诊断窗,是急性心肌梗死早期诊断较敏感和特异的血清标志物。

关 键 词:急性心肌梗死  心肌肌钙蛋白  肌酸激酶同工酶
文章编号:1009-881X(2006)02-0286-02
收稿时间:2006-02-15
修稿时间:2006-02-15

Significance of Cardiac Troponin Ⅰ in the early Diagnosis of Myocardial Infarction
WANG Ying-chao. Significance of Cardiac Troponin Ⅰ in the early Diagnosis of Myocardial Infarction[J]. Chinese Journal of Hemorheology, 2006, 16(2): 286-287
Authors:WANG Ying-chao
Affiliation:Department of Laboratory medicine,Suzhou Municiple Hospital,Suzhou 215008,China
Abstract:Objective To investigate the early diagnostic value and significance of cardiac troponin I (cTnI) and CK-MB in acute myocardial infarction (AMI).Methods Serum from 50 patients with coronary heart disease (AMI) and 50 healthy were examined for cTnI and CK-MB. Results In the 3h after AMI, the positive rates of cTnI 94.0% were significantly higher than CK-MB.24.0%, in the 5 day after AMI, the positive rates were 84.0% for cTnI and CK-MB were 6.0%.Conclusion The serum level of cTnI can closely reflect of myocardial dagmage in AMI. It provides a early diagnostic window. Serum level of cTnI is a marker high sensitivity and specificity for AMI and can aid in the early diagnosis of AMI.
Keywords:acute myocardial infarction (AMI)  Cardiac troponin I (cTnI)  CK-MB
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