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Apnea-hypopnea index in nonobese women with polycystic ovary syndrome |
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| Authors: | Hsiao-Ping Yang Jiunn-Horng Kang Hsiu-Yueh Su Wei-Min Liu Shih-Yi Huang |
| Institution: | a School of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan b Department of Obstetrics and Gynecology, Taipei Medical University, Taipei, Taiwan c Sleep Center, Taipei Medical University Hospital, Taipei, Taiwan d Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan e School of Medicine, Taipei Medical University, Taipei, Taiwan |
| Abstract: | ObjectiveTo assess the influence of polycystic ovary syndrome (PCOS) on respiratory events during sleep in nonobese Taiwanese women.MethodOvernight polysomnography was recorded in 18 nonobese women with PCOS who had not received treatment (body mass index BMI] 21.7 ± 0.57, age 29.1 ± 1.43 years) and in 10 age- and BMI-matched women without PCOS (BMI 20.9 ± 0.58, age 31.6 ± 3.87 years).ResultsThe nonobese women with PCOS had a higher total apnea-hypopnea index (AHI) especially during the non-rapid eye movement stage (AHINREM) than the women who did not have PCOS. The women with PCOS had higher serum levels of high-sensitivity C-reactive protein (hsCRP) and this was positively correlated with AHIREM. Total testosterone level was positively correlated with AHINREM, and androstenedione was negatively correlated with AHINREM.ConclusionPCOS was directly linked to increased obstructive respiratory events during sleep in nonobese women in Taiwan. |
| Keywords: | Androstenedione Apnea-hypopnea index Obstructive sleep apnea Polycystic ovary syndrome Testosterone |
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