Melanoma with unknown primary: report and analysis of 24 patients |
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| Authors: | Rita Clerico Ugo Bottoni Giovanni Paolino Marina Ambrifi Paola Corsetti Valeria Devirgiliis Stefano Calvieri |
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| Institution: | Clinica Dermatologica, Dipartimento di Medicina Interna e Specialità Mediche, University of Rome, La Sapienza, Viale del Policlinico, Rome, Italy. |
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| Abstract: | In the literature, there are some papers reporting on patients with metastatic melanoma from an unknown primary lesion (MUP). The pathogenesis of this phenomenon and the prognosis of these patients are still debatable. Therefore, we reviewed our casistics on MUP patients. We identified 24 MUP patients out of all patients registered into a melanoma database from June 1996 to June 2011. The incidence was 1.4?%. We compared the survival rate of all patients with MUP stage III-IV with all patients with metastatic melanoma known primary (MMKP) stage III-IV observing a clear survival improvement for MUP patients in front of MMKP patients (p?
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