12672例子宫颈液基细胞学诊断结果分析

目的:利用液基薄层细胞技术(TCT)对12 672例宫颈标本进行细胞学检测,探讨宫颈癌的发病情况及TCT在妇科疾病诊断中的意义。方法:2006年2月～2008年2月进行宫颈细胞学检测的12 672例宫颈标本采用液基薄层细胞技术制片,根据《子宫颈细胞学Bethesda报告系统》(TBS)诊断系统做出诊断,并对结果进行回顾性分析。结果:12 672例宫颈标本中,发现鳞癌13例,占0.103%;腺癌3例,占0.024%;高度鳞状上皮内病变(HSIL)64例,占0.505%;低度鳞状上皮内病变(LSIL)146例,占1.152%,其中伴人乳头瘤病毒(HPV)感染90例,占0.710%;非典型鳞状细胞(ASC)651例,占5.137%;非典型腺细胞(AGUS)107例,占0.844%;未见上皮内病变细胞或恶性细胞(NILM)11 688例,占92.235%。结论:TCT和TBS系统能全面准确地反映宫颈病变的情况。早期发现癌前病变、早期治疗,阻止病变升级是防治宫颈癌的关键。

Analysis on diagnostic results of Thin Prep cytological test of 12672 cases

Objective:To explore the prevalence situation of cervical carcinoma and diagnostic significance of ThinPrep cytological test(TCT) in gynecological diseases.Methods:12 672 cervical samples were detected by TCT from February 2006 to February 2008,then diagnosis was made according to TBS,and the results were analysed retrospectively.Results:Among 12 672 samples,the proportions of squamous cell carcinoma,adenocarcinoma,high grade squamous intraepithelial lesion(HSIL),low grade squamous intraepithelial lesion (LSIL),atypical squamous cells(ASC) and atypical glandular cells(AGUS) were 0.103%(13 cases),0.024%(3 cases),0.505% (64 cases),1.152%(146 cases),5.137%(651 cases) and 0.844%(107 cases),respectively.Among 146 cases of LSIL,90 cases (0.710%) were complicated with human papillomavirus infection.11 688 cases were normal,without intraepithelial lesion cells or malignant cells,accounting for 92.235%.Conclusion:TCT and TBS can reflect cervical lesions accurately and wholly.Early detection of precancerous lesions,early treatment and blocking the evolving of CIN are the key to preventing cervical cancer.