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| 褐藻多糖对糖尿病小鼠血糖影响的研究 | |
| 引用本文： | 徐宏亮,赵晓云,李明天,邱广斌,关一夫. 褐藻多糖对糖尿病小鼠血糖影响的研究[J]. 临床军医杂志, 2009, 37(6): 943-945 |
| 作者姓名： | 徐宏亮 赵晓云 李明天 邱广斌 关一夫 |
| 作者单位： | 1. 中国医科大学,生物化学与分子生物学教研室,辽宁,沈阳,110001 2. 沈阳药科大学 3. 中国科学院全属研究所,辽宁,沈阳,110016 4. 解放军第202医院,辽宁,沈阳,110003 |
| 摘 要： | 目的探讨褐藻多糖的降糖效果。方法链脲佐菌素复制小鼠糖尿病模型,检测小鼠血糖及血脂相关指标。结果(1)褐藻多糖灌胃14 d对正常小鼠血糖及血脂无显著影响(P>0.05)。(2)褐藻多糖能够降低糖尿病小鼠血糖,治疗第21天时检测到小鼠血糖的降低,下降11.3%,血糖浓度一直维持在治疗后的第32天,下降21.1%,与对照组相比有统计学意义(P<0.05)。(3)褐藻多糖对血脂未升高的糖尿病小鼠的血脂无明显影响(P>0.05)。结论褐藻多糖能有效降低STZ致糖尿病小鼠血糖。 |
| 关 键 词： | 褐藻多糖 糖尿病 血糖 血脂 |
Effect of Fucoidin on Blood Glucose in a Diabetic Mouse Model |
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| Xu Hong-liang,Zhao Xiao-yun,Li Ming-tian,Qiu Guang-bin,Guan Yi-fu. Effect of Fucoidin on Blood Glucose in a Diabetic Mouse Model[J]. Clinical Journal of Medical Officer, 2009, 37(6): 943-945 | |
| Authors: | Xu Hong-liang Zhao Xiao-yun Li Ming-tian Qiu Guang-bin Guan Yi-fu |
| Affiliation: | Xu Hong-liang1,Zhao Xiao-yun2,Li Ming-tian3,Qiu Guang-bin4,Guan Yi-fu1(1.Department of Biochemisty and Molecular Biology,China Medical University,Shenyang 110001,China,2.Shengyang Pharmaceutical University,3.Institute of Metal Research,Chinese Academy of Sciences,Shenyang 110016,4.202nd Hospital,PLA,Shenyang 110003,China) |
| Abstract: | Objective To evaluate the role of fucoidin in hypoglycemic activity.Methods Blood glucose and blood lipid level of experimental diabetic mouse model induced by Streptozotocin were assessed.Results 1 There is no effect on the blood glucose and blood lipid level of the normal mice administered by fucoidin for 14 days(P>0.05).2 The blood glucose level of the diabetic mice can be reduced by 11.3 % on the 21d after administered by fucoidin continuously.Furthermore,the blood glucose level of the diabetic mice mai... |
| Keywords: | fucoidin diabetes blood glucose blood lipid |
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