膝关节融合治疗股骨远端侵袭性骨巨细胞瘤

目的：探讨应用自体腓骨移植联合膝关节融合治疗股骨远端侵袭性骨巨细胞瘤的应用及临床效果。方法：自2007-2009年对5例股骨远端侵袭性骨巨细胞瘤（Campanacci Ⅲ级）行整块切除术后骨缺损，采用游离腓骨移植联合钢板内固定行膝关节融合术重建下肢功能。结果：所有患者随访20～80个月，疼痛症状消失，MSTS评分21～27分，骨愈合时间6—18个月，无移植骨吸收和骨折，恢复正常工作劳动。所有患者均未出现病变复发及肺转移。结论：肿瘤整块切除联合腓骨移植膝关节融合术是治疗股骨远端侵袭性骨巨细胞瘤的一种良好选择。

Resection Arthrodesis for Aggressive Giant Cell Tumor of the Distal Femur

Objective： To discuss the clinical methods and effects of resection arthrodesis for treatment of giant cell tumor （GCT） of the distal femur. Methods： 5 patients with Campanacci Grade Ⅲ giant cell tumors at the distal femur were treated with wide resection and arthrodesis using free fibular graft and plate from 2001 to 2009. Results： All of the patients were followed up for 20-40 months. The score of MSTS was 21-27 points. Bone graft healing occurred from 8-18 months and there was no pain, grafting bone resorption or fracture happed. All the patients were able to perform activities of daily living and to work without local recurrence or pulmonary metastasis noted. Conclusion： Wide resection and arthrodesis in aggressive GCTs of the distal femur with involvement of all muscle compartments is a good treatment option.