119例恶性血液病患者医院感染分析

目的：探讨恶性血液病医院感染的危险因素、病原体种类、感染部位等。方法：对119例恶性血液病患者医院感染进行回顾性调查分析。结果：119例恶性血液病患者化疗发生医院感染62例，占52．1％，以呼吸道感染最常见（46．0％），病原学以革兰阴性杆菌最多（55．1％），其次是真菌（23．0％）。粒细胞缺乏组感染率82．8％，非粒细胞缺乏组感染率42．2％。结论：化疗、粒细胞缺乏、大量使用抗生素是医院感染、真菌感染常见的危险因素。

Analysis of nosocomial infection in 119 patients with hematological malignant disease

Objective：To study the risk factors, pathogen classes and the infection locations in patients with hematological malignant diseases. Methods：Nosocomial infections in 119 patients with hematological malignant diseases were analyzed retrospectively. Results：Sity-two cases developed nosocomial infection after doing chemotherapy,and the proportion was 52.1% ,Respiratory infection was the most common infection location,and the ratio was 46.0%. The infection rate of the gram-negative bacilli was 55.1% ,the fungus was 23.0%. The infection rate of patients with agranulocytosis was 82.8 %,while the non-agranulocytosis group had the rotio of 42.2 %. Conclusion zChemotherapy, agranulocytosis and over applying the antibiotics were the main factors of nosocomial infection.