冠心病介入治疗后再狭窄因素分析

目的　探讨冠心病介入治疗后再狭窄与冠心病易患因素关系。方法 冠心病介入治疗440例中，选择连续84例(n5个狭窄病变)术后随访冠脉造影复查者，冠脉定量分析(QCA)术前、术后和随访复查冠脉造影图象，并分析再狭窄与冠心病易患因素的关系。 结果 患者6个月再狭窄率为40.00%,多元回归分析再狭窄发生时间与吸烟史、多个易患因素、多支病变、病变类型和前降支病变呈正性相关，与支架置入呈负性相关。 结论 冠心病易患因素与介入后再狭窄发生有密切的关系，特别是吸烟史。

Risk Factors of Coronary Heart Disease in Correlation with Restenosis after Transluminal Coronary Angioplasty and Stenting

Objective The purpose of this study is to determinate whether risk factors such as cigarette smoking, diabetes mellitus, hypertension, hypercholesterolaemia, and family history of coronary artery disease (CAD) are correlated with restenosis after coronary angioplasty. Methods Quantitative coronary analysis was made and angiographic characteristics of the lesions were determined in 84 patients with the angiographies of pre-intervention, post - intervention among 440 patients who had undertaken coronary angioplasty or coronary stenting. Angiographic restenosis was defined as at least 50% diameter stenosis on the follow-up angiogram after the initial successful procedure. A multivariable Cox regression was performed to assess factors correlated with restenosis. Results The rate of restenosis of all patients was 40.00 % during 6 months. The patients with coronary restenosis had more than one risk factor of CAD. Restenosis was correlated positively with pre- procedure smoking and other risk factors, multivessel disease, lesion types and LDA involvement negatively with stent implantation. Conclusion Restenosis after angioplasty might correlate significantly with pre- procedure smoking, and other risk factors of CAD.