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细皱香薷叶的化学成分研究
引用本文:刘莹,李喜凤,刘艾林,李志宏,杜冠华,秦海林.细皱香薷叶的化学成分研究[J].中草药,2009,40(9):1356-1359.
作者姓名:刘莹  李喜凤  刘艾林  李志宏  杜冠华  秦海林
作者单位:1. 河南中医学院,河南,郑州,450008;中国医学科学院北京协和医学院,药物研究所,中草药物质基础与,资源利用教育部重点实验室,北京,100050
2. 河南中医学院,河南,郑州,450008
3. 中国医学科学院北京协和医学院,药物研究所,中草药物质基础与,资源利用教育部重点实验室,北京,100050
摘    要:目的 研究细皱香薷Elsholtzia rugulosa叶的化学成分.方法 采用柱色谱法进行分离和纯化,通过波谱分析鉴定结构.结果 从乙醇提取物中分离得到了12个化合物,鉴定结构分别为洋芹索-7-O-β-D-葡萄糖苷(Ⅰ)、木犀草素-7-O-β-D-葡萄糖苷(Ⅱ)、刺槐素-7-O-β-D-葡萄糖苷(Ⅲ)、木犀草素-7-O-(6"-乙酰基)-β-D-葡萄糖苷(Ⅳ)、苯甲醇-β-D-葡萄糖苷(Ⅴ)、prunasin(Ⅵ)、β-谷甾醇(Ⅶ)、桦木酸(Ⅷ)、2α-羟基乌苏酸(Ⅸ)、2α-羟基齐墩果酸(Ⅹ)、洋芹素(Ⅺ)和木犀草素(Ⅻ).结论 化合物Ⅰ、Ⅲ、Ⅳ、Ⅸ和Ⅹ为首次从该种植物中分离得到.

关 键 词:细皱香薷  黄酮  三萜
收稿时间:2008/12/26 0:00:00

Chemical constituents from leaves of Elsholtzia rugulosa
LIU Ying,LI Xi-feng,LIU Ai-lin,LI Zhi-hong,DU Guan-hua and QIN Hai-lin.Chemical constituents from leaves of Elsholtzia rugulosa[J].Chinese Traditional and Herbal Drugs,2009,40(9):1356-1359.
Authors:LIU Ying  LI Xi-feng  LIU Ai-lin  LI Zhi-hong  DU Guan-hua and QIN Hai-lin
Institution:Henan College of Traditional Chinese Medicine,Zhengzhou 450008,China;Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Beijing 100050,China;Henan College of Traditional Chinese Medicine,Zhengzhou 450008,China;Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Beijing 100050,China;Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Beijing 100050,China;Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Beijing 100050,China;Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Beijing 100050,China
Abstract:Objective To study the chemical constituents from the leaves of Elsholtzia rugulosa.Methods Compounds were isolated and purified by silica gel column and Sephadex LH-20 chromatography.Their chemical structures were identified by spectral data.Results Twelve compounds were isolated,purified,and identified as:apigenin-7-O-β-D-glucopyranoside(Ⅰ),luteolin-7-O-β-D-glucopyranoside(Ⅱ),acacetin-7-O-β-D-glucopyranoside(Ⅲ),luteolin-7-O-(6"-acetyl)-β-D-glucopyranoside(Ⅳ),benzyl alcohol-β-D-glucopyranoside(Ⅴ),prunasin(Ⅵ),β-sitosterol(Ⅶ),betulinic acid(Ⅷ),corosolic acid(Ⅸ),maslinic acid(Ⅹ),apigenin(Ⅺ)and luteolin(Ⅻ).Conclusion Compounds Ⅰ,Ⅲ,Ⅳ,Ⅸ,and Ⅹ are obtained from this plant for the first time.
Keywords:Elsholtzia rugulosa Hemsl    flavonoids  triterpenes
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