肝硬化患者四项凝血指标检测和临床意义

目的：探讨肝硬化患者四项凝血指标的变化和临床意义。方法：对本院2006年1月～2007年11月收治的48例肝硬化患者进行凝血酶原时间（PT）、纤维蛋白原（FIB）、活化部分凝血活酶时间（APTT）、凝血酶时间（TT）的检测,检测设备为ACL-200贝克曼血凝仪。结果：48例患者的PT、APTT、TT均明显延长,FIB明显下降,与相关文献报道的结果相吻合。结论：凝血四项指标的变化较准确的反应了肝硬化患者的凝血功能状况,为临床对患者的病情评价、治疗和疗效观察提供了科学依据。

Four coagulation indicators in patients with liver cirrhosis and clinical significance of detection

Objective：To investigate the four coagulation indicators in patients with liver cirrhosis and clinical significance of the changes. Methods：To detect the prothrombin time（PT） ,fibrinogen（FIB） ,activated partial thromboplastin time（APTT） and thrombin time（TT） of the 48 cases of liver cirrhosis treated patients from Jan.2006 to Nov.2007,tested equipment for the ACL-200 coagulometer Beckman. Results：48 cases of patients with PT,APTT,TT were significantly prolonged,FIB decreased,and related literature reported results. Conclusion：The four indicators of changes in blood coagulation are more accurate reflection of the blood coagulation in patients with liver cirrhosis status,for clinical evaluation of the patient ′s condition,treatment and observe the effect provides a scientific basis.