| 酪蛋白磷酸肽钙磷复合体对粘性放线菌生长影响的实验研究 |
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| 引用本文： | 徐皑,刘兴容,李艳萍.酪蛋白磷酸肽钙磷复合体对粘性放线菌生长影响的实验研究[J].现代预防医学,2010,37(1). |
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| 作者姓名： | 徐皑 刘兴容 李艳萍 |
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| 作者单位： | 泸州医学院附属口腔医院,泸州,646000 |
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| 基金项目： | 四川泸州市科委科技计划项目资助 |
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| 摘 要： | 目的]研究酪蛋白磷酸肽钙磷复合体(Casein phosphopeptide-Amorphic Calcium Phosphate,CPP-ACP)对粘性放线菌生长的影响,探讨CPP-ACP作为一种生物防龋制剂的可行性.方法]将粘性放线菌ATCC19246在BHI培养基中厌氧培养,在实验组中加入不同浓度(0.5%～5.0%(W/V))的CPP-ACP溶液,厌氧培养48 h后采用噻唑蓝(MTT)比色分析法测定细菌浓度的吸光度A值(γ=550 nm).结果]随CPP-ACP浓度的升高,粘性放线菌甲臜产物的二甲亚砜溶液的吸光度值降低,即粘性放线菌的活菌数减少(P＜0.01).结论]CPP-ACP对粘性放线菌生长具有抑制作用,且随CPP-ACP浓度的升高抑制作用增强.
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| 关 键 词： | 粘性放线菌 抑制 |
EXPERIMENTAL STUDY OF CASEIN PHOSPHOPEP TIDE-AMORPHIC CALCIUM PHOS-PHATE ON THE GROWTH OF ACTINOMYCES VISCOSUS |
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| XU Ai,LIU Xing-rong,LI Yan-ping.EXPERIMENTAL STUDY OF CASEIN PHOSPHOPEP TIDE-AMORPHIC CALCIUM PHOS-PHATE ON THE GROWTH OF ACTINOMYCES VISCOSUS[J].Modern Preventive Medicine,2010,37(1). |
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| Authors: | XU Ai LIU Xing-rong LI Yan-ping |
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| Institution: | XU Ai,LIU Xing-rong,LI Yan-ping. (Dental Hospital of Luzhou Medical College,Luzhou 646000,China) |
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| Abstract: | Objective] To investigate the effects of casein phosphopeptide-amorphic calcium phosphate (CPP-ACP) on the growth of Actinomyces viscosus,then evaluate the possibility of CPP-ACP as an effective biological anti-caries agent. Methods] Actinomyces viscosus ATCC19246 were incubated in BHI which contain different concentration of CPP-ACP and cultured in anerobic condition for 48 hours. Colorimetric assay was used for assay of survival of Actinomyces viscosus. Results] With the concentration of CPP-ACP increa... |
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| Keywords: | CPP-ACP |
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