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Stereoselective binding of doxazosin enantiomers to plasma proteins from rats,dogs and humans in vitro
Authors:Jia-an SUN  De-zhi KONG  Ya-qin ZHEN  Qing LI  Wei ZHANG  Jiang-hua ZHANG  Zhi-wei YIN  Lei-ming REN
Affiliation:[1]Institute of Chinese Integrative Medicine, Hebei Medical University, Shijiazhuang 050071, China [2]Bethune International Peace Hospi-tal, Shijiazhuang 050081, China
Abstract:doxazosin enantiomer stereoselectivity plasma protein binding equilibrium dialysis species difference pharmacokinetics benign prostatic hyperplasia lower urinary tract symptom al-adrenoceptor
Keywords:doxazosin  enantiomer  stereoselectivity  plasma protein binding  equilibrium dialysis  species difference  pharmacokinetics  benign prostatic hyperplasia  lower urinary tract symptom  al-adrenoceptor
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