| 艾灸治疗溃疡性结肠炎疗效及对肠上皮细胞HLA-DR抗原的影响 |
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| 引用本文： | 吴焕淦,潭卫林.艾灸治疗溃疡性结肠炎疗效及对肠上皮细胞HLA-DR抗原的影响[J].针刺研究,1999,24(1):12-16. |
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| 作者姓名： | 吴焕淦 潭卫林 |
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| 作者单位： | 上海市针灸经络研究所!上海200030(吴焕淦，陈汉平，施征，华雪桂 )，上海长征医院!上海200003(潭卫林 ) |
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| 摘 要： | 临床研究共收治慢性溃疡性结肠炎 １５１例，随机分成隔药灸 Ⅰ组（６５例）、隔药灸Ⅱ组（５６例）和对照组（３０例），其中隔药灸 Ⅰ组，近期痊愈率达 ５３．８％，总有效率为 ９２．３％；隔药灸 Ⅱ组，近期痊愈５０．０％，总有效率为８９．３％；对照组，近期痊愈率３０．０％，总有效率为６６．７％。其作用机理可能是通过抑制和／或消除肠上皮细胞ＨＬＡ－ＤＲ抗原的表达，增加（强）Ｔ_８~＋细胞数与功能，调整Ｔ淋巴细胞亚群间的比例关系而使结肠粘膜病变得以有效地纠正。
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| 关 键 词： | 溃疡性结肠炎 隔药饼灸 HLA-DR抗原 T细胞亚群 |
Effect of Moxibustion on Ulcerative Colitis and Expression of HLA-DR Antigen on Epithelial Cell of the Colon |
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| Abstract: | 151 patients with ulcerative colitis were divided randomly into herbal cake-separated moxibustion group Ⅰ (65 cases), herbal cake-separated moxibustion group Ⅱ (56 cases)and drug group (30 cases)as a control. A good clinical result was obtained. The short-term curative rate was 53. 8 per cent in herbal cake-separated moxibustion group Ⅰ,50. 0 per cent in herbal cake-separated moxibustion group Ⅱ and 30. 0 per cent in drug group. The effective mechanism of treatment may be relevant to depressing or eliminating the antigenic expression of HLA-DR in colonic epithelial cell, increasing the amount of T_8~+ cells, correcting the proportion of the subgroups of T lymphocyte, and resulting in the improvement of the injured intestinal mucosa. |
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