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| Incidence and predictive value of congenital hypertrophy of retinal pigment epithelium in Chinese familial adenomatous polyposis patients. | |
| 引用本文： | Dennis S.C. Lam,Samuel P.Y. Kwok,Alvin K.H. Kwok. Incidence and predictive value of congenital hypertrophy of retinal pigment epithelium in Chinese familial adenomatous polyposis patients.[J]. 中华医学杂志(英文版), 1998, 111(3): 278-281 |
| 作者姓名： | Dennis S.C. Lam Samuel P.Y. Kwok Alvin K.H. Kwok |
| 作者单位： | Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China,Department of Surgery, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China,Department of Anatomical & Cellular Pathology, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong, China,Department of Chemical Pathology, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong, China |
| 摘 要： | ＩｎｃｉｄｅｎｃｅａｎｄｐｒｅｄｉｃｔｉｖｅｖａｌｕｅｏｆｃｏｎｇｅｎｉｔａｌｈｙｐｅｒｔｒｏｐｈｙｏｆｒｅｔｉｎａｌｐｉｇｍｅｎｔｅｐｉｔｈｅｌｉｕｍｉｎＣｈｉｎｅｓｅｆａｍｉｌｉａｌａｄｅｎｏｍａｔｏｕｓｐｏｌｙｐｏｓｉｓｐａｔｉｅｎｔｓＤｅｎｎ... |
Incidence and predictive value of congenital hypertrophy of retinal pigment epithelium in Chinese familial adenomatous polyposis patients |
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| Dennis S.C. Lam,Samuel P.Y. Kwok,Alvin K.H. Kwok,C.T. Liew,Joseph W.Y. Lau,Calvin C.P. Pang. Incidence and predictive value of congenital hypertrophy of retinal pigment epithelium in Chinese familial adenomatous polyposis patients[J]. Chinese medical journal, 1998, 111(3): 278-281 | |
| Authors: | Dennis S.C. Lam Samuel P.Y. Kwok Alvin K.H. Kwok C.T. Liew Joseph W.Y. Lau Calvin C.P. Pang |
| Affiliation: | 1. Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China 2. Department of Surgery, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China 3. Department of Anatomical & Cellular Pathology, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong, China 4. Department of Chemical Pathology, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong, China |
| Abstract: | Objective To investigate the incidence and predictive value of congenital hypertrophy of retinal pigment epithelium (CHRPE) in the Chinese familial adenomatous polyposis (FAP) patients.Methods Eleven FAP patients and 28 at risk relatives from 7 families were examined for CHRPE lesions. Results CHRPE was present in all 11 FAP patients. Nine CHRPE lesions were found in 9 of the 28 at risk relatives. There were great intra and inter-familial variations of the CHRPE lesions. Two at risk relatives were diagnosed to have FAP only after our screening and subsequent proctosigmoidoscopy. Nine at risk relatives were put under high surveillance because of the presence of CHRPE. Conclusion The incidence of CHRPE in the FAP patients in our study is 100%. Eye examination for CHRPE for FAP patients and their at risk relatives is of very high value. A central FAP registry is thus recommended. |
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