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Long-term local control of recurrent adenoid cystic carcinoma in the parotid gland with radiotherapy and intraarterial infusion chemotherapy
Authors:Terashima Koutarou  Shioyama Yoshiyuki  Nakamura Katsumasa  Ohga Saiji  Nomoto Satoshi  Yamaguchi Toshihiro  Toba Takashi  Yoshitake Tadamasa  Yabuuchi Hidetake  Nakashima Torahiko  Terashima Hiromi  Honda Hiroshi
Affiliation:(1) Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan;(2) Department of Otolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;(3) Department of Radiation Technology, School of Health Sciences, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Abstract:We report a case of postoperative recurrence of adenoid cystic carcinoma in the left parotid gland treated with radiotherapy and arterial infusion chemotherapy. A 52-year-old woman had a history of surgical resection for an adenoid cystic carcinoma arising from the left parotid gland 25 years before. Despite two reoperations for local recurrence after the initial surgery, she had a third local recurrence in the remnant of the left parotid gland. The patient was treated with a concurrent combination of radiotherapy (60 Gy/30F) and intraarterial infusion chemotherapy with carboplatin (750 mg/30 days) from which she obtained a complete response. The patient has remained free of local progression 54 months after treatment. Radiotherapy and arterial infusion chemotherapy is effective treatment for local recurrence of adenoid cystic carcinoma in the head and neck.
Keywords:Adenoid cystic carcinoma  Radiotherapy  Intraarterial chemotherapy
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