低管电压扫描技术用于CT引导下冷冻消融治疗肝癌的可行性

目的 观察低管电压扫描技术用于CT引导下冷冻消融治疗肝癌的可行性。方法 以21例接受常规CT扫描(管电压120 kV)引导下冷冻消融的肝癌患者(A组),前瞻性对23例肝癌患者行低管电压(100 kV)CT引导下冷冻消融(B组)。对2组均于消融治疗前、后以自动管电流模式(50~450 mA)行CT扫描,并以自适应统计迭代重建(ASIR)算法(重建百分比均为40%)重建图像;对比2组治疗前、后CT图像质量主、客观评价结果,以及疗效和患者辐射剂量[容积CT剂量指数(CTDIvol)]。结果 组间CT图像质量主、客观评价结果及疗效差异均无统计学意义(P均>0.05)。治疗前、后A组患者CTDIvol均显著高于B组(P均<0.001)。结论 低管电压扫描技术可用于CT引导下冷冻消融治疗肝癌;联合ASIR算法可在保证图像质量和不影响评估冷冻消融效果的同时降低辐射剂量。

Feasibility of low tube voltage scanning technology in CT-guided cryoablation therapy of liver cancer

Objective To observe the feasibility of low tube voltage scanning technology in CT-guided cryoablation therapy of liver cancer. Methods Twenty-one patients who underwent routine CT (tube voltage 120 kV)-guided cryoablation of liver cancer (group A) were retrospectively enrolled, while low tube voltage (100 kV) CT-guided cryoablation of liver cancer was prospectively performed in 23 patients (group B). CT scanning were performed before and after ablation with automatic tube current mode (50-450 mA), and adaptive statistical iterative reconstruction (ASIR) algorithm was used for image reconstruction (reconstruction percentages of 40%) of both groups. The subjective scores and objective evaluations of CT image quality before and after treatment were compared between groups, so as the treatment effect and patient''s radiation dose (volume CT dose index [CTDIvol]). Results No significant difference of subjective scores, objective evaluations of CT image quality nor treatment effect was detected between groups(all P>0.05). Before and after treatment, CTDIvol of patients in group A was significantly higher than that in group B (btoh P<0.001). Conclusion Low tube voltage scanning technology could be used for CT-guided cryoablation of liver cancer, which might ensure image quality without affecting evaluation on cryoablation effect and reduce radiation dose combined with ASIR algorithm.