糠酸莫米松乳膏联合保湿霜治疗婴幼儿过敏性皮炎的有效性和安全性

探讨糠酸莫米松软膏与保湿霜对婴儿皮肤过敏性皮炎的疗效和安全性。方法 选取2021年 6月-2022年5月黄骅市人民医院收治的130例过敏性皮炎患儿，随机分为观察组与对照组，每组65例。对照 组外涂0.1%糠酸莫米松乳膏进行治疗，观察组外涂糠酸莫米松乳膏联合保湿霜进行治疗，比较两组临床疗 效、临床症状和皮损程度、生活质量及不良反应发生情况。结果 观察组治疗总有效率为96.92%，高于对 照组的78.46%，差异有统计学意义（P＜0.05）；两组临床症状评分、皮损程度评分均低于治疗前，且观察 组低于对照组（P ＜0.05）；两组治疗后IDQOL评分低于治疗前，且观察组低于对照组（P ＜0.05）；观察 组不良反应发生率为7.69%，低于对照组的18.46%，差异无统计学意义（P ＞0.05）。结论 1%糠酸莫米松软 膏与保湿霜配合使用对婴幼儿皮炎的治疗效果优于单独使用1%糠酸莫米松软膏，可有效改善患者临床症 状和皮损程度，提高其生活质量，且不易复发，安全性较好，值得临床应用。

Efficacy and Safety of Mometasone Furoate Cream Combined with Moisturizing Cream in the Treatment of Infantile Allergic Dermatitis

To investigate the efficacy and safety of mometasone furoate cream and moisturizing cream in the treatment of infantile allergic dermatitis. Methods A total of 130 children with allergic dermatitis admitted to Huanghua Municipal People''s Hospital from June 2021 to May 2022 were randomly divided into observation group and control group, with 65 children in each group. The control group was treated with 0.1% mometasone furoate cream, and the observation group was treated with mometasone furoate cream combined with moisturizing cream. The clinical efficacy, clinical symptoms and skin lesions, quality of life and adverse reactions were compared between the two groups. Results The total effective rate of treatment in the observation group was 96.92%, which was higher than 78.46% in the control group, and the difference was statistically significant (P <0.05). The clinical symptom score and skin lesion score of the two groups were lower than those before treatment, and the observation group were lower than those in the control group (P <0.05). After treatment, the IDQOL score of the two groups was lower than those before treatment, and that in the observation group was lower than that in the control group (P <0.05). The incidence of adverse reaction in the observation group was 7.69%, which was lower than 18.46% of the control group, but the difference was not statistically significant (P >0.05). Conclusion The therapeutic effect of 1% mometasone furoate cream combined with moisturizing cream on infantile dermatitis is better than that of 1% mometasone furoate cream alone. It can effectively improve the clinical symptoms and skin lesions of patients, improve their quality of life, and is not easy to relapse, which is safe and worthy of clinical application.