| 对《中国药典》2005年版一部栀子药材中栀子苷含量测定方法的探讨 |
| |
| 引用本文： | 雷鹏,刘韶,李新中,谭志国,李静. 对《中国药典》2005年版一部栀子药材中栀子苷含量测定方法的探讨[J]. 中药新药与临床药理, 2007, 18(3): 225-227 |
| |
| 作者姓名： | 雷鹏 刘韶 李新中 谭志国 李静 |
| |
| 作者单位： | 中南大学湘雅医院药剂科,长沙,410008 |
| |
| 摘 要： | 目的改进栀子药材中栀子苷的含量测定方法。方法比较了2005年版《中国药典》方法和改进方法。用HPLC法测定栀子苷含量,流动相为乙腈-水(15∶85),检测波长为238nm。结果采用50%甲醇为提取溶剂的改进方法所测定栀子中栀子苷含量要明显高于药典法。结论改进的方法准确、简便,可为新版药典中栀子的含量测定方法提供参考依据。
|
| 关 键 词： | 栀子 栀子苷 含量测定 |
| 文章编号： | 1003-9783（2007）03-0225-03 |
| 收稿时间： | 2007-01-22 |
| 修稿时间： | 2007-01-22 |
Discussion on Assay of Geniposide in Fructus Gardeniae in Chinese Pharmacopoeia (2005 Edition) Volume I |
| |
| LEI Peng,LIU Shao,LI Xinzhong,TAN Zhiguo,LI Jing. Discussion on Assay of Geniposide in Fructus Gardeniae in Chinese Pharmacopoeia (2005 Edition) Volume I[J]. Traditional Chinese Drug Research & Clinical Pharmacology, 2007, 18(3): 225-227 |
| |
| Authors: | LEI Peng LIU Shao LI Xinzhong TAN Zhiguo LI Jing |
| |
| Affiliation: | Pharmacy Department of Xiangya Hospital, Central South University, Changsha 410008 |
| |
| Abstract: | Objective To improve the method for determination of geniposide in Fructus Gardeniae.Methods The improved method was compared with the pharmacopoeia method.The content of geniposide was determined by HPLC at 238nm detection wavelength with acetonitrile-water(15:85)as mobile phase .Results The improved method in which 50 % methanol was used as solvent was superior to the pharmacopoeia method in which methanol was adopted as solvent.A higher geniposide content was abtained from the former.Conclusion The improved method is convenient and accurate,and can be used to supply reference evidence for the assay of Fructus Gardeniae in the new edition of pharmacopoeia. |
| |
| Keywords: | HPLC |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
