益气活血方对慢性萎缩性胃炎患者血浆胃动素及促胃液素的影响

[目的]探讨益气活血方对慢性萎缩性胃炎(CAG)患者血浆促胃液素(GAS)、胃动素(MOT)的影响.[方法]将200例CAG患者随机分为治疗组120例及对照组80例.治疗组服用益气活血方,对照组采用猴头菌提取物(谓葆),对幽门螺杆菌阳性者加用西药三联综合疗法治疗,疗程均为3个月.治疗前后,应用放射免疫法批量检测2组病例的血浆GAS、MOT水平,进行自身前后对照与组间对照统计学分析.[结果]2组患者治疗后血浆GAS、MOT平均水平较治疗前明显升高(P＜0.05或＜0.01),且治疗组水平明显高于对照组(P＜0.05).[结论]益气活血方具有提高CAG患者血浆GAS、MOT水平,促进其胃肠功能的作用.

Influence of Yiqihuoxue Decoction on plasma gastrin and motilin in patients with chronic atrophic gastritis

[Objective]To explore the effect of Yiqihuoxue Decoction on plasma gastrin(GAS) and motilin(MOT) in the patients of chronic atrophic gastritis(CAG).[Methods]Two hundred cases of CAG were randomly divided into treatment group(120 cases) and control group(80 cases).According to management guidelines for CAG,patients in the control group were given conventional treatment,and patients in the treatment group were given Yiqihuoxue Decoction.Before and after treatment,radioimmunoassay was used to detect GAS and MOT motilin levels of the cases in 2 groups.Comparison and statistical analysis were made.[Results]Plasma GAS and MOT of the 2 groups after treatment were significantly higher than that before treatment(P<0.05 or<0.01),and they were significantly higher in the treatment group than in the control group(P<0.05).[Conclusion]Yiqihuoxue Decoction can increase GAS and MOT levels of patients with CAG and improve the gastrointestinal function.