| 芳香化酶抑制剂致骨质疏松研究进展 |
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| 引用本文： | 马翠翠. 芳香化酶抑制剂致骨质疏松研究进展[J]. 国际肿瘤学杂志, 2008, 35(10): 771-774 |
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| 作者姓名： | 马翠翠 |
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| 作者单位： | 福建省中医学院研究生部,福州,350014 |
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| 摘 要： | 乳腺癌患者服用芳香化酶抑制剂(AI)使得卵巢功能缺失导致体内雌激素水平下降,从而加速骨代谢发生骨质疏松.在临床中应给予重视并根据具体情况选择适当防治手段.推荐使用钙剂+维生素D、双膦酸盐、选择性雌激素受体调节剂、中药等药物治疗,减少骨质疏松的发病率.
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| 关 键 词： | 乳腺肿瘤 芳香酶抑制剂 雌激素类 骨质疏松 |
Research of aromatase inhibitor induced osteoporosis |
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| MA Cui-cui. Research of aromatase inhibitor induced osteoporosis[J]. Journal of International Oncology, 2008, 35(10): 771-774 |
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| Authors: | MA Cui-cui |
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| Abstract: | Breast cancer patients treated by aromatase inhibitor(AI) may cause ovarian failure, resulting in decreased hormone levels. Then bone loss increases, which may result in thinning bone and osteoporosis. In clinic, attention should be given and appropriate means must be chosen to prevent and treat this disease. Calcium + vitamin D, diphosphonate, selective estrogen receptor modulator, Chinese medicine are recommen-ded to reduce the incidence of esteoporosis. |
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| Keywords: | Breast neoplasms Aromatase inhibitors Estrogens Osteoporosis |
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