Widespread transfer of resistance genes between bacterial species in an intensive care unit: implications for hospital epidemiology |
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| Authors: | Naiemi Nashwan Al Duim Birgitta Savelkoul Paul H M Spanjaard Lodewijk de Jonge Evert Bart Aldert Vandenbroucke-Grauls Christina M de Jong Menno D |
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| Affiliation: | Academic Medical Center, Department of Medical Microbiology, Amsterdam, The Netherlands. |
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| Abstract: | A transferable plasmid encoding SHV-12 extended-spectrum beta-lactamase, TEM-116, and aminoglycoside resistance was responsible for two sequential clonal outbreaks of Enterobacter cloacae and Acinetobacter baumannii bacteria. A similar plasmid was present among isolates of four different bacterial species. Recognition of plasmid transfer is crucial for control of outbreaks of multidrug-resistant nosocomial pathogens. |
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