| 900MHz微波电磁辐射对大鼠大脑皮质神经元神经递质受体γ-氨基丁酸蛋白表达的影响 |
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| 引用本文： | 王强,曹兆进,白雪涛. 900MHz微波电磁辐射对大鼠大脑皮质神经元神经递质受体γ-氨基丁酸蛋白表达的影响[J]. 卫生研究, 2005, 34(5): 546-548 |
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| 作者姓名： | 王强 曹兆进 白雪涛 |
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| 作者单位： | 中国疾病预防控制中心环境与健康相关产品安全所,北京,100021 |
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| 摘 要： | 目的研究900MHz微波电磁辐射对原代培养大鼠大脑皮质神经元神经递质γ-氨基丁酸(GABA)受体表达的影响。方法将大鼠大脑皮质神经元暴露于900MHz的连续性微波电磁辐射(SAR=1.15~3.22W/kg),进行每天2h、连续6d暴露及一次性12h暴露,以GABA受体蛋白表达为观察指标,研究微波对神经元的兴奋性影响。结果微波电磁辐射影响神经元GABA受体表达。结论微波电磁辐射对神经元兴奋性影响可能存在“窗口效应”。
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| 关 键 词： | 微波 神经元 GABA受体 窗口效应 |
| 文章编号： | 1000-8020（2005）05-0546-03 |
| 收稿时间： | 2004-11-18 |
| 修稿时间： | 2004-11-18 |
Effect of 900MHz electromagnetic fields on the expression of GABA receptor of cerebral cortical neurons in postnatal rats |
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| Wang Qiang,Cao Zhao-jin,Bai Xue-tao. Effect of 900MHz electromagnetic fields on the expression of GABA receptor of cerebral cortical neurons in postnatal rats[J]. Journal of hygiene research, 2005, 34(5): 546-548 |
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| Authors: | Wang Qiang Cao Zhao-jin Bai Xue-tao |
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| Affiliation: | National Istitute of Evironmental Health and Related Product Safety, China CDC, Beijing 100021, China. |
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| Abstract: | OBJECTIVE: To investigate the effects of 900 MHz microwave electromagnetic fields (EMF) on the expression of neurotransmitter GABA receptor of cerebral cortical neurons in postnatal rats. METHODS: Neurons were exposed to 900 MHz continuous microwave EMF (SAR = 1.15 - 3.22mW/g) for 2 hours per day in 6 consecutive days and for 12 hours at one time. GABA receptor was chosen to be the biological end. RESULTS: Significant changes had been observed in exposed neurons in the expression of GABA receptor. (P < 0.01) . CONCLUSION: The expression of GABA receptor of neurons were significantly regulated by 900 MHz microwave, and a power "window" effect was observed in the exposed neurons. |
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| Keywords: | microwaves, neuron, GABA receptor, power “window" effect |
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