谈羊膜移植在角膜和眼表疾病应用中的问题

由于羊膜具有抗炎、抗纤维化、抗新生血管生成、促进角膜修复的作用,羊膜已经成为治疗角膜和眼表疾病的理想材料.随着羊膜广泛应用于角膜和眼表疾病,在某种程度上改变了一些角膜及眼表疾病传统的治疗方式,但随之而来的临床问题也逐渐显露,主要体现在：适应证如何把握;手术如何进行个体化设计;如何观察术后并发症和术后规范用药等问题.在此,谈些个人的经验和看法,以期使羊膜移植手术能在临床治疗角膜和眼表疾病中发挥更好的作用.

Amniotic membrane transplantation in corneal and ocular surface diseases

The amniotic membrane has been shown to have anti-inflammatory,anti-fibrotic,anti-angiogenic properties and ability to provide a substrate for the growth of corneal and conjunctival epithelial cells,and it is an ideal material for ocular surface reconstruction.The treating patten of corneal and ocular surface diseases has changed due to the widespread using of amniotic membrane transplantation,but there are a lot of problems in the application of amniotic memebrane in clinic,such as how to grasp indications and reduce the failure rate,how to apply individual skill for different patients with corneal disease,and how to observe postoperative complicationsm and reasonably use medicine after operation.This paper give some personal experience and opinion in orde to achieve better effects in treatment of corneal and ocular surface diseases using amniotic membrane transplantation.