吸毒人群中MTB与HIV感染关系的调查

目的　了解吸毒人群 (海洛因依赖者 )感染人类免疫缺陷病毒和结核分支杆菌的情况及其关系。方法　对广东省内某吸毒人群进行艾滋病抗体检测、结核菌素皮肤试验、胸部X线平片检查以及社会人口学调查。结果　在 80 3例吸毒者中检出 6 1例艾滋病抗体阳性者 ,检出率为 7 6 % ;399例吸毒者的结核菌素皮肤试验阳性率为 6 7 2 % (2 6 8/399) ,强阳性反应率为 2 1 3% (85 /399) ;35例结核菌素皮肤试验反应强阳性者胸部X线平片检查 ,发现有结核病灶的占 94 3% (33/35 )。结论　吸毒人群的HIV、MTB感染率和患病率均比普通人群高 ,吸毒 (共用针具传播HIV)—感染HIV—并发结核病形成一个相互促进的关系。表明控制艾滋病和结核病已成为目前公共卫生迫切要解决的问题。

Investigation on Relationship Between MTB and HIV Infection in Drug Users

ObjectiveTo look into the infection status of human immunodeficiency virus(HIV) and mycobacterium tuberculosis(MTB) in drug users(heroin dependant)and the relationship between HIV and MTB.MethodsA group of drug users from Guangdong province are tested for HIV antibody,tuberculin skin test with purified protein derivatives(PPD),chest radiographs and socio-demograph survey.ResultsSixty-one(7.6%) cases out of 803 drug users were positive anti-HIV;thepositive rate of tuberculin skin test with PPD in 399 drug users was 67.2%(268/399) and 21.3%(85/399) were with strong positive reaction;94.3%(33/35) of 35 cases with strong positive PPD reaction were found with micobacterium tuberculosis focus in their chest radiographs.ConclusionThe infection rate of HIV and MTB in drug users was higher than that of normal population.A relation of mutual accelerating is formed by drug use (sharing needles),HIV infection and tuberculosis complications.The control of HIV tuberculosis became a urgent task in public health.