颅内不同靶点定向毁损术后的小脑症状与手术灶的关系

目的：评价并探讨立体定向毁损颅内不同靶点治疗帕金森病（PD）术后出现小脑体征与手术灶关系。方法：随机抽出颅内3个不同靶点毁损治疗PD共90例进行回顾性分析。所有病例均采用Leksell定向仪，选择常规靶点。结果：丘脑外侧苍白球（VpLp）毁损术后一周以上出现小脑体征者占3．3％，在丘脑腹测中间校（Vim）毁损出现小脑体征者占6．6％。而毁损丘脑腹外侧核（VL）出现率最高。结论：毁损灶越靠近丘脑脑底部，术后出现小脑症状的发生率越高，说明走向毁损灶的位置与小脑症状的出现有着很大的关系。

The relationship between intracranial stereotactic lesions and their postoperative cerebellar signs

Object To discuss and assess the relationship between intracranial stereotractic lesions and their postoperative cerebellar signs. Method Randomly choosing the cases of 3 different taopts in Vplp, Vim and VL nucleus distroyed by stereotactic surgery used Leksell-G stereotactic appatus, retrospective analysis was performed in 90 pestoperative cases with parkinson disease. Result Cerebellar sign occured in patients with lesions at Vplp was 3. 3%, lesions at Vim was 6. 6% and lesions at VL had a highest incidence. Conclusion The closer the destructive lesion is to the subthalamus, the higher the incidence of cerebellar sign is The location of the destructive lesion is close correlated with the incidence of postoperative cerebellar signs.