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基质金属蛋白酶及其抑制剂与食管癌浸润转移的研究进展
引用本文:林建清,林若柏. 基质金属蛋白酶及其抑制剂与食管癌浸润转移的研究进展[J]. 中华肿瘤防治杂志, 2003, 10(6): 663-666
作者姓名:林建清  林若柏
作者单位:福建医科大学附属第二医院肿瘤科,福建,泉州,362000;福建医科大学附属协和医院肿瘤科,福建,福州,350004
摘    要:正常体内基质金属蛋白酶 (MMPs)及其抑制剂 (TIMPs)保持平衡状态 ,许多研究表明MMPs与TIMPs系统在食管癌的浸润及转移方面发挥重要作用 ,可能成为一个新的有价值的食管癌预后指标

关 键 词:食管肿瘤/病理学  金属蛋白酶类组织抑制剂  预后  综述文献
文章编号:1009-4571(2003)06-0663-04
修稿时间:2003-01-07

Progress in Reserch of MMPs/TIMPs System in Esophageal Cancer
LIN Jian qing,LIN Ruo bai. Progress in Reserch of MMPs/TIMPs System in Esophageal Cancer[J]. Chinese Journal of Cancer Prevention and Treatment, 2003, 10(6): 663-666
Authors:LIN Jian qing  LIN Ruo bai
Affiliation:LIN Jian qing,LIN Ruo bai.Department of Oncology,The Second Affiliated Hospital .Fujian Medical University,Quanzhou 362000,China
Abstract:The balance between MMPs and tissue inhibitors of metalloproteinase (TIMPs) is keeping normally in human body.Many of studies showed that the MMPs/TIMPs system played an important role in the invasion and metastasis of esophageal canser,This suggests that MMPs/TIMPs system be a new valuable prognostic maker.
Keywords:esophageal neoplasms/pathology  tissue inhibitor of metalloproteinases  prognosis  review literature
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