152例药品不良反应报告分析

目的:了解我院ADR发生的规律和特点,为临床合理用药提供参考。方法:对我院2012-2013年收集到的药品不良反应(ADR)报告进行整理,分类统计和分析相关影响因素:患者性别、年龄、给药途径、药品种类、ADR累及器官或系统及其临床表现等。结果:15岁及以下少年儿童发生ADR的比例高,达44.08%;静脉滴注给药引起的ADR最多,占95.39%;抗菌药物引起的ADR最多,占55.26%;ADR的临床表现多见皮肤及其附件损害,占68.42%。结论:临床应加强ADR的报告和监测工作,为临床合理用药开展有效的服务和监管工作,尽力减少或避免药品不良反应的发生。

Analysis of 162 Cases of ADR Reports

OBJECTIVE： To investigate the regularity and characteristics of ADR in our hospital, and to provide reference for rational drug use in the clinic. METHODS： ADR reports collected from our hospital during 2012- 2013 were classified and analyzed statistically in respects of patients＇ gender, age, routes of administration, category of drug, organs or systems involved in ADR and clinical manifestations. RESULTS： Children under 15 years old took up high proportion, accounting for 44.08%; most of ADR were caused by intravenous drip, accounting for 95.39% ; antibiotics-induced ADR accounted for 55.26%. The clinical manifestations of ADR were mainly lesion of skin and its appendants, accounting for 68.42%. CONCLUSIONS： Great importance should be attached to ADR reporting and monitoring so as to provide effective service and monitoring for rational drug use, and reduce or avoid the occurrence of ADR as soon as possible.