Comparison of rates of and charges from pregnancy complications in users of extended and cyclic combined oral contraceptive (COC) regimens: a brief report期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Comparison of rates of and charges from pregnancy complications in users of extended and cyclic combined oral contraceptive (COC) regimens: a brief report

Authors:	Brandon Howard James Trussell ElizaBeth Grubb Maureen J Lage

Institution:	1. Teva Global Medical Affairs, Frazer, PA 19355, USA;2. Princeton University, Princeton, NJ 08544, USA;3. University of Hull, Hull HU6 7RX, England;4. Teva Global Health Economics and Outcomes Research, Kansas City, MO 64131, USA;5. Health Metrics Outcomes Research, Bonita Springs, FL 34134, USA

Abstract:	Objective To evaluate pregnancy complication rates and related charges in users of 84/7, 21/7 and 24/4 combined oral contraceptives (COCs). Study design Data were obtained from the i3 InVision Data Mart™ retrospective claims database. Subjects were aged 15–40 years, first prescribed a COC between 1/1/2006 and 4/1/2011 and continuously insured for ≥ 1 year. 84/7 users were matched 1:1 to 21/7 and 24/4 users. Results Pregnancy-related complication rates and associated charges were significantly lower with 84/7 vs. 21/7 and 24/4 regimens. Conclusion Preliminary data suggest 84/7 regimens may be associated with fewer pregnancy complications and lower related charges.

Keywords:	Hormonal contraception Pregnancy rates 84/7 21/7 24/4 regimens
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