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Positron emission tomography
Authors:Y. Lucas Yamamoto  Christopher J. Thompson  Mirko Diksic  Ernst Meyer  William H. Feindel
Affiliation:(1) Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada;(2) Neuroisotope Laboratory, Montreal Neurological Institute, 3801 University Street, Room 636, H3A 2B4 Montreal, Quebec, Canada
Abstract:Summary One of the most exciting new techniques introduced in the last ten years is positron emission tomography (PET). PET provides quantitative, three-dimensional images for the study of specific biochemical and physiological processes in the human body. This approach is analogous to quantitativein vivo autoradiography but has the added advantage of permitting non-invasivein vivo studies. PET scanning requires a small cyclotron to produce short-lived positron emitting isotopes such as oxygen-15, carbon-11, nitrogen-13 and fluorine-18.Proper radiochemical facilities and advanced computer equipment are also needed. Most important, PET requires a multidisciplinary scientific team of physicists, radiochemists, mathematicians, biochemists and physicians. This review analyses the most recent trends in imaging technology, radiochemistry, methodology, and clinical applications of positron emission tomography.Reproduced with kind permission of Pergamon Press from the special issue of Radiation Physics and Chemistry on Radiation and Medicine (1984). Guest Editors: B. C. Lentle and H. Singh.
Keywords:Clinical application  imaging techniques  methodology  positron emission tomography  radiochemistry
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