| 近亲婚配现状及后代遗传效应初探 |
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| 引用本文： | 王军荣,刘志婷,续微,关宝杰. 近亲婚配现状及后代遗传效应初探[J]. 中国妇幼保健, 2006, 21(14): 1944-1945 |
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| 作者姓名： | 王军荣 刘志婷 续微 关宝杰 |
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| 作者单位： | 吉林大学第一医院,吉林,长春,130021 |
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| 摘 要： | 目的:探讨近亲婚配现状及遗传效应,避免近亲婚配。方法:对近亲婚配引起反复流产、死胎或生育智力低下儿者,采用细胞遗传学技术,进行染色体检查,并对其进行核型分析。结果:检查夫妻之一核型异常的占5%,其后代核型异常占5%;夫妻双方核型正常,但反复流产、死胎或生后死亡的占90%。结论:不能排除近亲婚配是造成反复流产及后代异常的重要原因之一。
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| 关 键 词： | 近亲婚配 不良妊娠 遗传效应 |
| 文章编号： | 1001-4411（2006）14-1944-02 |
| 修稿时间： | 2005-12-21 |
The actuality of consanguineous marriage and the offspring genetic effect |
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| WANG Jun- Rong, LIU Zhi- Ting, XU Wei,et al.. The actuality of consanguineous marriage and the offspring genetic effect[J]. Maternal and Child Health Care of China, 2006, 21(14): 1944-1945 |
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| Authors: | WANG Jun- Rong LIU Zhi- Ting XU Wei et al. |
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| Affiliation: | The First Hospital of Jilin University , Changchun 130021, Jilin, China |
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| Abstract: | Objective:To analyze the actuality of consanguineous marriage and the offspring genetic effect.Methods:By the technique of cytogenetics,to analyze the chromosome of couples those who had the history of repeatedly abortion or childbearing history of dead foetus or mental retardation because of consanguineous mating.Results:The percentage of abnormal karyotype in one of a couple and in offspring were both 5%,and the percentage of couples both of whom had normal karyotype,but had the history of repeatedly abortion or dead foetus or postnatal death was 90%.Conclusion:It can not be eliminated that consanguineous marriage is an important reason that causing repeatedly abortion and abnormal offspring. |
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| Keywords: | Consanguineous marriage Ill-pregnancy Genetic effect |
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