| HLA单倍型相合骨髓移植的骨髓粒单祖细胞和造血功能的动态观察 |
| |
| 引用本文： | 张缙鸾,韩璐,温丙昭,李玲,马艳.HLA单倍型相合骨髓移植的骨髓粒单祖细胞和造血功能的动态观察[J].新疆医科大学学报,1993(1). |
| |
| 作者姓名： | 张缙鸾 韩璐 温丙昭 李玲 马艳 |
| |
| 作者单位： | 新疆医学院第一附属医院血液科，新疆医学院第一附属医院血液科，新疆医学院第一附属医院血液科，新疆医学院第一附属医院血液科，新疆医学院第一附属医院血液科 |
| |
| 摘 要： | 本文报告1例HLA单倍型相合急性淋巴细胞白血病骨髓移植成功造血功能恢复情况。通过与HLA相合者比较,HLA单倍型相合骨髓移植后不影响骨髓粒单祖细胞(CFU-GM)和造血功能恢复速度;急性严重移植物抗宿主病(GVHD)可抑制CFU-GM生长和造血功能的恢复。骨髓CFU-GM测定不但是骨髓移植植活的最早观察指标,而且可能是骨髓抑制的最早反应。
|
| 关 键 词： | HLA单倍型相合骨髓移植 粒单组细胞 造血功能 移植物抗宿主病 |
A Kinetic Study of Granulocytic-monocyte Progenitor Compartment and Hematopoietic Function in HLA-haploidentical Bone Marrow Transplantation |
| |
| Zhang Jinluan,et al.A Kinetic Study of Granulocytic-monocyte Progenitor Compartment and Hematopoietic Function in HLA-haploidentical Bone Marrow Transplantation[J].Journal of Xinjiang Medical University,1993(1). |
| |
| Authors: | Zhang Jinluan |
| |
| Institution: | Zhang Jinluan,et al Department of Hematology,First Affiliated Hospital,Xiniang Medical edical College |
| |
| Abstract: | This article reports a continuance of regular kinetic observation of the recovery of granulocyticmonocyte colony forming cell (CFU-GM) in bone marrow and hematopoietic function on one case of acute lymphoid leukemia before and after HLA-haloidentical bone marrow transplantation. Comparing this case with HLA-identical bone marrow transplantation, we discover three phenomena which were as follows: One was that HLA-haploidentical bone marrow transplantation does not affect the speed of recovery of CFU-GM and hematopoietic function, another was that acute severe GVHD can supress both the growth of CFU-GM and the recovery of hemotopoietic function, and the last one was that the measurement of CFU-GM of bone marrow was not only the most early and valuable sign of successful bone marrow transplantation but also the earlist reaction of restraint of bone marrow. |
| |
| Keywords: | HLA-haploidentical bone marrow transplantation CFU-GM hematopoietic function GVHD |
| 本文献已被 CNKI 等数据库收录！ |
