| 肝硬化患者外周血B细胞和T细胞及其亚群的研究 |
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| 引用本文： | 张云燕,刘洪月. 肝硬化患者外周血B细胞和T细胞及其亚群的研究[J]. 淮海医药, 2004, 22(1): 12-13 |
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| 作者姓名： | 张云燕 刘洪月 |
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| 作者单位： | 江苏省连云港市第一人民医院,检验科,222002;江苏省连云港市第一人民医院,检验科,222002 |
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| 摘 要： | 目的 探讨了肝硬化患者外周血 B细胞和 T淋巴细胞及其亚群的变化。方法 应用单克隆技术测定了 33例肝硬化患者外周血 B细胞和 T淋巴细胞亚群的水平并以 30名正常健康人作比较。结果 肝硬化患者外周血B细胞数显著地高于正常人组 (P<0 .0 0 1 ) ,CD3、CD4 、CD4 / CD8显著地低于正常人 (P<0 .0 1 )。结论 肝硬化患者是一种自身免疫调节异常的疾病
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| 关 键 词： | 肝硬化 B淋巴细胞 T淋巴细胞亚群 |
| 文章编号： | 1008-7044(2004)01-0012-02 |
| 修稿时间： | 2003-03-18 |
Study of B and T lymphocytes and T subgroups in peripheral blood of patients with hepatocirrhosis |
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| ZHANG Yun yan,LIU Hong yue.. Study of B and T lymphocytes and T subgroups in peripheral blood of patients with hepatocirrhosis[J]. Journal of Huaihai Medicine, 2004, 22(1): 12-13 |
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| Authors: | ZHANG Yun yan LIU Hong yue. |
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| Abstract: | Objective To study the changes of B and T lymphocytes and T subgroups in peripheral blood of patients with hepatocirrhosis.Methods Immunological technique was employed to detect B and T as well as T subgroups of lymphocytes in peripheral blood of 33 patients with hepatocirrhosis and 30 normal controls.Results B lymphocytes were extremely higher than those in normal controls( P <0.001).But CD 3,CD 4 and CD 4/CD 8 were obviously lower( P <0.01).Conclusion Hepatocirrhosis is a kind of selfimmunity disease with abnormal immmunoregulation. |
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| Keywords: | Hepatocirrhosis B lymphocyte T lymphocyte subgroups |
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