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变性高效液相色谱在肿瘤基因检测的研究进展
引用本文:张丹妍,张丹媚[综述],李练兵,马明福[审校]. 变性高效液相色谱在肿瘤基因检测的研究进展[J]. 中国优生与遗传杂志, 2012, 0(10): 8-9
作者姓名:张丹妍  张丹媚[综述]  李练兵  马明福[审校]
作者单位:[1]重庆市人口和计划生育科学技术研究院,出生缺陷与生殖健康重庆市市级重点实验室,重庆市正鼎司法鉴定所,重庆400020 [2]重庆房地产职业学院,重庆401331
摘    要:介绍变性高效液相色谱(DHPLC)技术在肿瘤基因检测的临床应用,以及用于肿瘤基因突变和基因多态性检测的情况,以期为肿瘤的基因检测提供重要信息。

关 键 词:DHPLC  肿瘤  p53基因  表皮生长因子  STR多态性

Research progress of denaturing high performance liquid chromatography in tumor gene detection
ZHANG Dan-yan,ZHANG Dan-mei,Overview,LI Lian-bing,MA Ming-fu. Research progress of denaturing high performance liquid chromatography in tumor gene detection[J]. Chinese Journal of Birth Health & Heredity, 2012, 0(10): 8-9
Authors:ZHANG Dan-yan  ZHANG Dan-mei  Overview  LI Lian-bing  MA Ming-fu
Affiliation:ZHANG Dan-yan,ZHANG Dan-mei,Overview,LI Lian-bing,MA Ming-fu,Revision.(1.Population and Family Planning of Chongqing Science and Technology Research Institute,Birth Defects and Reproductive Health of the Key Laboratory of Chongqing,Chongqing Zheng-Ding Judicial Identification Institute,Chongqing 400020;2.Chongqing Real Estate College,Chongqing 401331)
Abstract:To introduce the denaturing high performance liquid chromatography(DHPLC) technology in tumor gene and detection of clinical applications and for tumor gene mutation and polymorphism detection,in order to provide important information for gene detection.
Keywords:DHPLC  Tumor  p53 gene  Epidermal growth factor  STR polymorphism
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