| 吸烟对男性不育患者精子DNA完整性及精子形态的影响分析 |
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| 引用本文： | 刘安娜,王厚照.吸烟对男性不育患者精子DNA完整性及精子形态的影响分析[J].中国优生与遗传杂志,2012(10):118-118,67. |
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| 作者姓名： | 刘安娜 王厚照 |
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| 作者单位： | 中国人民解放军第一七四医院检验科,福建厦门361003 |
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| 摘 要： | 目的探讨吸烟对男性不育患者精子DNA完整性及精子形态的影响。方法 132例男性不育患者根据烟龄分为2组:A组烟龄1～5年;B组烟龄大于5年。正常对照组为100例非吸烟已生育健康男性。对其进行精子DNA完整性检测及精子形态学分析。结果 A组精子DNA碎片指数(DFI)和精子畸形率与正常对照组比较差异有显著性(P<0.05),而B组精子DNA碎片指数和精子畸形率与正常对照组比较差异有非常显著性(P<0.01)。结论长期吸烟可能会损伤男性精子DNA及影响精子形态,是引起男性不育的原因之一。
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| 关 键 词： | 吸烟 精子DNA完整性 精子形态 |
Effect of smoking on sperm DNA integrity and sperm morphology in male infertility patients |
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| LIU An-na,WANG Hou-zhao.Effect of smoking on sperm DNA integrity and sperm morphology in male infertility patients[J].Chinese Journal of Birth Health & Heredity,2012(10):118-118,67. |
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| Authors: | LIU An-na WANG Hou-zhao |
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| Institution: | .(The Clinical Lab Department of the 174th Hospital of PLA,Xiamen,361003) |
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| Abstract: | Objective： To investigate the effect of smoking on sperm DNA integrity and sperm morphology in male infertility patients.Methods： 132 cases of male infertility patients were divided into 2 groups： group A smoked 1 to 5 years;Group B smoked more than five years.Control group were 100 non-smoking male who already had their progenies.Analysis on sperm DNA integrity and sperm morphology were made.Results： DNA fragmentation index（DFI） and sperm deformity rate of group A were significantly higher than that of control group（P〈0.05）,and group B showed higher results（P〈0.01）.Conclusion： Long-term smoking may damage sperm DNA and affect sperm morphology,and thus is one of the causes of male infertility. |
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| Keywords: | Smoking Sperm DNA integrity Sperm morphology |
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