实时三维超声产前诊断胎儿典型面裂畸形的临床意义

目的探讨实时三维超声产前诊断胎儿面裂畸形的临床意义,寻求提高胎儿唇腭裂诊断准确性的有效方法。方法应用实时三维超声产前对面裂畸形;唇腭裂胎儿和正常胎儿唇腭部位的二维进行对照。结果 10例正常胎儿面部显示率100%,上牙槽突显示率100%,硬腭显示率70%(7/10)。10例唇腭裂胎儿包括7例单纯唇裂,2例上唇裂合并硬腭裂和1例唇裂合并软腭裂。实时三维诊断了所有7例单纯唇裂,诊断率100%;诊断了单侧唇裂合并腭裂1例,有1例单侧唇裂合并腭裂仅诊断了唇裂而漏诊了腭裂,诊断率70%(7/10),另外1例唇裂合并软腭裂仅诊断了唇裂而漏诊了软腭裂。结论实时三维超声产前诊断对胎儿唇裂,尤其是唇裂合并牙槽突及硬腭裂的诊断具有较大的应用价值,但是对胎儿未合并牙槽突裂的软腭裂及部分硬腭裂做出诊断,仍具有很大的难度。

Real - time 3D ultrasound prenatal diagnosisof the clinical significance of fetal typical facial cleft deformity

Objective ： To determine the value of Real - time 3D ultrasound prenatal diagnosis of the clinical significance of fetal for typical facial cleft deformity Improving the diagnosticaccuracy of fetal cleft lipand/or palate cleft. Methods ： Applieation of real - time three dimensional eehoeardiography prenatal fetal normal fetal cleft lip and palate cleft lip and palate parts of two - dimension control. Result： 10 cases of normal fetal lip display rates 100% , On alveolar show 100% , and palate, 70% （7/10）. 10 eases of fetal cleft lip and palate eleft lip includes 7 simple, merge hard on 1 case of cleft lip and palate and 1 eleft lip patients with cleft of soft palate. Real - time 3D diagnostic all 7 example simple cleft palates, diagnostic rate 100%. Diagnosis of unilateral cleft lip with cleft palate in 1 ease. There are 1 ease of unilateral cleft lip with cleft palate only diagnosis and missed diagnosis of cleft lip and cleft palate, diagnosed in 70% （ Seven - tenths）. 1 cases of cleft lip with cleft of soft palate only soft diagnosis and missed diagnosis of cleft lip and cleft palate. Conclusions： Real - time three dimensional echocardiography prenatal diagnosis of fetal cleft lip, especially hard and alveolar process cleft lip with cleft palate diagnostic has a large value, but on the fetus are not merged alveolar cleft of the soft palate and some of the hard palate to make diagnosis and still has a great deal of difficulty.