| Recurrent achalasia treated with Heller myotomy： A review of the literature |
| |
| 基金项目： | ACKNOWLEDGMENTS We are grateful to Professor Shi Yao Chen for his excellent assistance in statistical analysis. |
| |
| 摘 要： | AIM： To evaluate the efficacy and safety of Heller myotomy （HM） for recurrent achlasia, performed after different methods of first-line treatment. METHODS： We searched for studies published in PubMed from 1966 to March 2008 on treatment of recurrent achalasia with HM after failure with different methods of first-line treatment. The efficacy of HM was assessed by a pooled estimate of response rate with individual studies weighted proportionally to sample size. RESULTS： Sixteen studies were eligible and included in the review, The results showed that HM has a better remission rate for recurrent achalasia after failure of HM weighted mean （SD）] of 86.9% （21,8%） compared with 81.6% （23.8%） for pneumatic dilatation （PD）. One study evaluated the efficacy of HM after failure of PD combined with botulinum toxin injection （83%）, The most common complications were perforation and gastroesophageal reflux, CONCLUSION： HM has the best efficacy in patients with recurrent achiasia who were treated with HM as first-line treatment, Future studies should focus on how to increase the success rate and decrease the complications of HM.
|
| 关 键 词： | 回流失弛缓症 肌切开术 肝切除术 疗效 |
| 收稿时间： | 2008 Sep 4 |
Recurrent achalasia treated with Heller myotomy:A review of the literature |
| |
| Authors: | Lan Wang You-Ming Li |
| |
| Institution: | Lan Wang, You-Ming Li, Department of Gastroenterology, the First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou 310003, Zhejiang Province, China |
| |
| Abstract: | AIM: To evaluate the efficacy and safety of Heller myotomy (HM) for recurrent achlasia, performed after different methods of first-line treatment. METHODS: We searched for studies published in PubMed from 1966 to March 2008 on treatment of recurrent achalasia with HM after failure with different methods of first-line treatment. The efficacy of HM was assessed by a pooled estimate of response rate with individual studies weighted proportionally to sample size. RESULTS: Sixteen studies were eligible and included in the review. The results showed that HM has a better remission rate for recurrent achalasia after failure of HM weighted mean (SD)] of 86.9% (21.8%) compared with 81.6% (23.8%) for pneumatic dilatation (PD). One study evaluated the efficacy of HM after failure of PD combined with botulinum toxin injection (83%). The most common complications were perforation and gastroesophageal reflux. CONCLUSION: HM has the best efficacy in patients with recurrent achlasia who were treated with HM as first-line treatment. Future studies should focus on how to increase the success rate and decrease the complications of HM. |
| |
| Keywords: | Recurrent achalasia Holler myotomy Pneumatic dilatation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《世界胃肠病学杂志(英文版)》浏览原始摘要信息 |
