Alcohol study on blood concentration estimation: Reliability and applicability of Widmark formula on Chinese male population |
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| Institution: | 1. Unit for Psychiatric Research, Department of Clinical Research, University of Southern Denmark, Odense C, Denmark;2. Brain Research-Inter-Disciplinary Guided Excellence (BRIDGE), Department of Clinical Research, University of Southern Denmark, Odense C, Denmark;3. Amsterdam University Medical Centre, Department of Psychiatry, University of Amsterdam, Amsterdam, the Netherlands;4. Amsterdam Institute for Addiction Research, Department of Research, Arkin, Amsterdam, the Netherlands;1. Louvain Experimental Psychopathology research group (LEP), Psychological Sciences Research Institute, UCLouvain, Louvain-la-Neuve, Belgium;2. Stanford University, Department of Psychiatry and Behavioral Sciences, Stanford, CA, USA;3. Univ. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, Lille, France;4. CHU Lille, Clinique de Psychiatrie, CURE, Lille, France;5. Centre National de Ressources et de Résilience Lille-Paris (CN2R), Lille, France;6. Department of Adult Psychiatry, Saint-Luc Academic Hospital & Institute of Neuroscience, UCLouvain, Brussels, Belgium;7. Centre de Neurosciences Cognitives, UMR 5229, CNRS, Bron, France;8. Service Universitaire de Réhabilitation, SUR-CL3R, Centre Hospitalier Le Vinatier, Lyon, France |
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| Abstract: | Widmark formula suggests estimating blood alcohol concentration level (BAC) on a given amount of alcohol administrated with knowledge of subject’s body weight and sex. The idea has been referenced extensively in forensic science with application in drink driving prosecution. A sample of Chinese subjects was collected in the drinking experiment, and in this study we mainly focus on the verification of the validity of Widmark formula on Chinese male population. A promising result is obtained where the extrapolated BAC measurement is directly proportional to the amount of alcohol administrated, and inversely to the subject’s body weight. The results noted in the general linear model is further supported by the nonlinear regression analysis and a concordant argument reaches by deploying the concept to the BAC level attained at peak. |
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