Hospital-based study of the economic burden associated with rotavirus diarrhea in eastern China |
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Authors: | Jin Hui Wang Bei Fang Zhaoyin Duan Zhaojun Gao Qian Liu Na Zhang Lijie Qian Yuan Gong Sitang Zhu Qirong Shen Xiaona Wu Qingbin |
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Institution: | a Department of Epidemiology and Health Statistics, Southeast University, Nanjing 210009, China b Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Viral Gastroenteritis Division, Beijing 100052, China c Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China d Laboratory of Virology, Beijing Municipal Laboratory of Infection and Immunity, Capital Institute of Pediatrics, Beijing 100020, China e Guangzhou Children's Hospital, Guangzhou 510120, China f Children's Hospital of Fudan University, Shanghai 200032, China g Fujian Centers for Disease Control and Prevention, Fuzhou 350001, China h The Children's Hospital of Soochow University, Suzhou 215003, Jiangsu, China |
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Abstract: | Rotavirus infection is one of the most common causes of severe diarrhea in China. To evaluate the economic burden associated with rotavirus infection of children in China, we combined data on the disease burden of rotavirus-associated costs for samples comprising 832 outpatients and 604 inpatients from five seaside cities. The average social costs and direct medical costs for rotavirus-associated admissions were calculated to be US $61.64 and US $40.73 for outpatients, and US $684.15 and US $559.48 for inpatients, respectively, from October 1, 2006 to December 1, 2007. On average, the private cost ranged from US $54.64 for outpatients to US $454.24 for inpatients when children suffered from rotavirus infection. Accordingly, this cost accounted for 35.19-293% of the monthly income of an unskilled or service worker. We estimated that the annual number of children with rotavirus diarrhea was 12.10 million. Consequently, the total annual direct cost, total annual social cost, and total annual private cost were US $271.4 million, US $365.0 million, and US $290.0 million, respectively. Furthermore, rotavirus diarrhea affected children's behavior and emotions, which had a great influence on the caretakers’ quality of life. These data indicate the potential requirement for a safe and effective rotavirus vaccine to reduce the economic burden associated with rotavirus disease. |
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Keywords: | Rotavirus Economic burden Diarrhea China |
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