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Erdheim-Chester disease with intramuscular lipogranuloma
Authors:T Yamamoto  Kosaku Mizuno
Institution:(1) Department of Orthopaedic Surgery, Kobe University School of Medicine, 7-5-1-Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan, JP
Abstract:We report on a rare manifestation of Erdheim-Chester disease with intramuscular lipogranuloma. The patient was a 66-year-old man who noted a soft tissue mass in the right quadriceps femoris muscle. Radiographs revealed symmetrical osteosclerosis in the diametaphysis of both femora and tibiae. An open biopsy revealed a proliferation of lipid-laden histiocytes in the femoral bone marrow and the quadriceps femoris muscle. To our knowledge, this is the second case of Erdheim-Chester disease involving muscle. Received: 4 October 1999 Revision requested: 18 November 1999 Revision received: 1 December 1999 Accepted: 2 December 1999
Keywords:  Erdheim-Chester Disease  Lipogranuloma  MRI  Muscle  Rectus femoris
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