| 大鼠中缝背核和束旁核纤维联系特性的电生理学分析 |
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| 引用本文： | 黎箴辉,张桂林,黎旭文.大鼠中缝背核和束旁核纤维联系特性的电生理学分析[J].武汉大学学报(医学版),1989(3). |
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| 作者姓名： | 黎箴辉 张桂林 黎旭文 |
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| 作者单位： | 湖北医学院生理教研室，湖北医学院生理教研室，湖北医学院生理教研室 |
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| 摘 要： | 应用逆向激活碰撞技术并结合神经元电生理学特征分析,发现中缝背核有纤维直接投射到丘脑束旁核,且这些中缝-丘脑单位中约40%是5-羟色胺能神经元;束旁核对中缝背核活动也存在影响。讨论了两核团间联系性质及其在痛信号传递及调制中的意义。
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| 关 键 词： | 中缝核 丘脑腹内侧核 血清素 神经元 传入 电生理学 |
Electrophysiological Analysis of Connection Characteristics Between Nucleus Raphe Dorsal and Nucleus Parafascicularis in Rats |
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| Li Zhenhui,.Electrophysiological Analysis of Connection Characteristics Between Nucleus Raphe Dorsal and Nucleus Parafascicularis in Rats[J].Medical Journal of Wuhan University,1989(3). |
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| Authors: | Li Zhenhui |
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| Abstract: | The purpose of this paper is to study if the direct projections from nucleus raphe dorsal(NRD)to nucleus parafascicularis(Pf)exist by anti- dromic activation and collision technique and to distinguish the serotoner- gic(5-HT)projections from non-serotonergic projections based on electro- physiological specifics of NRD neurons.The results showed that during Pf stimulation fifteen neurons in NRD were antidromically activated and 40% of these neurons were serotonergic.Electrical acupuncture(EA)facilitated their spontaneous discharges.Moreover,Pf could influence the neuron acti- vities in NRD.The experiments suggest that there are many direct un- myelinated thin projections from NRD to thalamic Pf,among which 5-HT projections account for about 40%.It is possible that the NRD-Pf projec- tions have an important effect on pain modulation and EA analgesia. |
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| Keywords: | raphe nuclei ventromedial hypothalamic nucleus serotonin neurons afferent electrophysiology |
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