2010-2015年我国暗娼人群艾滋病病毒/梅毒/丙型病毒性肝炎感染状况分析

目的 了解我国2010-2015年暗娼人群艾滋病病毒（HIV）/梅毒/丙型病毒性肝炎（丙肝）抗体阳性率情况。方法 2010-2015年每年的4-6月，在全国艾滋病暗娼监测哨点开展连续横断面调查，通过匿名调查问卷收集调查对象基本人口学信息等，同时抽取静脉血进行HIV、梅毒和丙肝抗体检测，利用SPSS 18.0统计学软件进行数据整理和分析。结果 2010-2015年共监测暗娼1 180 926人，3种传染病抗体阳性率平均为HIV 0.25%（2 898/1 180 926）、梅毒2.54%（30 028/1 180 926）、丙肝0.72%（8 559/1 180 926），逐年3种疾病抗体阳性率呈现下降趋势。不同人口学特征的暗娼人群感染情况不同，31岁年龄组、少数民族、外籍，文化程度为小学及以下、婚姻状态为离异或丧偶的暗娼人群HIV、梅毒和丙肝抗体阳性率均较高。场所来源为街头的暗娼人群，HIV/梅毒/丙肝抗体阳性率均高于其他场所来源的暗娼人群，差异有统计学意义，分别为HIV（2=2 807.11，P0.01）、梅毒（2=8 230.48，P0.01）、丙肝（2=778.30，P0.01）。多元logistic回归分析显示，吸毒（OR=17.82，95%CI:16.02~19.82）、初中及以下文化程度（OR=1.79，95% CI:1.58~2.03）、场所来源是街头/路边店（OR=2.74，95% CI:2.40~3.13）的暗娼感染HIV的风险较高。结论 我国暗娼人群整体梅毒抗体阳性率较高，31岁、文化程度较低和收入较低的街头低档暗娼HIV、梅毒和丙肝抗体阳性率均高于其他组暗娼人群。

Prevalence of HIV infection,syphilis and hepatitis C in female sex workers in China, 2010-2015

Objective To understand the prevalence of HIV infection,syphilis and hepatitis C in female sex workers (FSWs) in China from 2010 to 2015,and provide scientific evidence for the prevention and control of HIV infection,syphilis and hepatitis C in this population.Methods Consecutivecross-sectional survey with uniformed anonymous questionnaire was conducted in FSWs during the sentinel surveillance,their basic demographic information and blood samples were collected.Statistical software SPSS 18.0 was used for data processing and analysis.Results A total of 1 180 926 FSWs were surveyed from 2010 to 2015.The average prevalence was 0.25％ for HIV infection (2 898/1 180 926),2.54％ for syphilis (30 028/1 180 926) and 0.72％ for hepatitis C (8 559/1 180 926),which declined with year.The prevalence differed in FSWs with different demographic characteristics,the prevalence HIV infection,syphilis and hepatitis C were high in FSWs who were aged ≥ 31 years,in minority ethnic group,foreigners,with primary school education level or below,divorced and widowed.The prevalence were higher in street FSWs than in other FSWs,the differences were significant (x2 =2 807.11,P ＜0.01 for HIV infection,x2 =8 230.48,P ＜ 0.01 for syphilis and x2 =778.30,P ＜ 0.01 for hepatitis C).Multivariate logistic regression analysis showed that drug use (OR =17.82,95％ CI:16.02-19.82),low educational level (OR =1.79,95％ CI:1.58-2.03),being street roadside FSWs (OR =2.74,95％ CI:2.40-3.13) were high risk factors for HIV infection.Conclusion The prevalence of syphilis in FSWs was high in China.The prevalence of HIV infection,syphilis and hepatitis C were higher in FSWs who were aged ≥31 years,less educatedand low paid than other FSWs.