| 老年髓系抗原阳性急性淋巴细胞白血病1例报告并文献分析 |
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| 引用本文： | 苏永宏,焦宁超. 老年髓系抗原阳性急性淋巴细胞白血病1例报告并文献分析[J]. 临床医药实践, 2011, 20(9): 647-649 |
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| 作者姓名： | 苏永宏 焦宁超 |
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| 作者单位： | 北京顺义区医院,北京,101300 |
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| 摘 要： | 目的:提高对老年髓系抗原阳性急性淋巴细胞白血病(M y+ALL)的认识。方法:报告1例老年髓系抗原阳性M y+ALL患者的临床资料和实验室检查特征、治疗经过、预后并结合文献复习讨论。结果:患者骨髓原幼淋巴细胞占42.5%,CD 7+细胞占86.99%,cCD 3+细胞占77.24%,CD 33+占91.87%,CD 13+占11.80%,M PO,CD 117,CD 22,CD 19,CD 20,CD 34均阴性,给予长春新碱+柔红霉素+泼尼松(VDP方案)化疗1周期,未缓解,之后给予长春新碱+泼尼松+阿克拉霉素+阿糖胞苷(VP+AA方案)化疗2周期达缓解。结论:老年髓系M y+ALL恶性程度高,对常规化疗方案治疗无效,需给予兼顾髓系和淋系的化疗方案为宜。
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| 关 键 词： | 白血病 淋巴细胞 急性 髓系抗原阳性 |
Myeloid antigen-positive acute lymphoblastic leukemia in the elderly |
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| SU Yong-hong,JIAO Ning-chao. Myeloid antigen-positive acute lymphoblastic leukemia in the elderly[J]. Proceeding of Clinical Medicine, 2011, 20(9): 647-649 |
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| Authors: | SU Yong-hong JIAO Ning-chao |
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| Affiliation: | (Shunyi Hospital of Beijing,Beijing 101300,China) |
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| Abstract: | Objective:To enhance the knowledge of myeloid antigen-positive My+ALL in the elderly.Methods:To report a case of myeloid antigen-positive My+ALL in the elderly,including clinical features,treatment and prognosis and the related literature was reviewed.Results:Myeloid antigen-positive ALL was diagnosed by 42.5% prolymphocyte in bone marrow,86.99% expressed CD7+,77.24% cCD3+,91.87% CD33,11.80% CD13+but none MPO,CD117,CD22,CD19,CD20 and CD34.VDP regimen were administered with no effect,VP+AA regimen achieved complete remission after two periods.Conclusion:Myeloid antigen-positive ALL in the elderly has a fulminant course with poor response to chemontherapy.The chemotherapy regimens were for ALL. |
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| Keywords: | leukemia lymphocytic acute myeloid antigen-positive |
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