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蛰虫抗大鼠免疫性肝纤维化研究
引用本文:袭柱婷,栾希英,李珂珂,姜学连,单长民. 蛰虫抗大鼠免疫性肝纤维化研究[J]. 中西医结合心脑血管病杂志, 2001, 0(4)
作者姓名:袭柱婷  栾希英  李珂珂  姜学连  单长民
作者单位:山东滨州医学院
摘    要:目的 :研究蛰虫抗肝纤维化的作用。方法 :以腹腔注射猪血清制备大鼠肝纤维化模型 ,以ALT、GGT、TP、Alb、A /G比值、IV .C、LN、HA及肝脏组织病理变化为指标 ,观察蛰虫对大鼠肝纤维化的影响。结果 :蛰虫能提高肝纤维化大鼠TP、ALb含量及A/G比值 ,有降低ALT、GGT、IV .C、LN、HA的作用 ,并能改善肝脏组织病理学变化。结论 :蛰虫有保护肝细胞、减轻肝细胞变性坏死 ,恢复肝细胞结构和功能 ;减少纤维组织增生 ,阻止纤维化发展 ,促进纤维组织降解的作用

关 键 词:蛰虫  大鼠  肝纤维化

Experimental Study on Eupolyphaga Seu Steleophaga Treating Hepatic Fibrosis
Xi Zhuting,Luan Xiying,Li Keke,et al. Experimental Study on Eupolyphaga Seu Steleophaga Treating Hepatic Fibrosis[J]. Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, 2001, 0(4)
Authors:Xi Zhuting  Luan Xiying  Li Keke  et al
Affiliation:Binzhou Medical College.Binzhou 256603
Abstract:Objective:To study the effects of eupolyphaga seu steleophaga on hepatic fibrosis.Methods:The rat immunohepatic fibrosis model was made by intraperitoneal injection of porcine serum and treated with eupolyphaga seu steleophaga.The ALT?GGT?TP?ALb?A/G?IV.C?LN?HA and the pathological change of the liver were observed,Results:Eupolyphaga seu steleophaga could increase TP?ALb?A/G,decrease ALT?GGT?IV.C?LN?HA and improve the pathological change.Conclusions:Eupolyphaga seu steleophaga could protect hepatic cells,alleviate degeneration and necrosis,recover structure and function,and reduce the proliferation of fibrous tissue.
Keywords:Eupolyphaga Seu Steleophaga Rat Hepatic Fibrosis
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